Induction of Multiple miR-200/182 Members in the Brains of Mice Are Associated with Acute Herpes Simplex Virus 1 Encephalitis

Anna Majer; Kyle A. Caligiuri; Kamilla K. Gale; Yulian Niu; Clark S. Phillipson; Timothy F. Booth; Stephanie A. Booth

doi:10.1371/journal.pone.0169081

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Open Access

Peer-reviewed

Research Article

Induction of Multiple miR-200/182 Members in the Brains of Mice Are Associated with Acute Herpes Simplex Virus 1 Encephalitis

Anna Majer,

Affiliations Department of Medical Microbiology and Infectious Diseases, College of Medicine, Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada, Molecular PathoBiology, National Microbiology Laboratory, Canadian Science Centre for Human and Animal Health, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
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Kyle A. Caligiuri,

Affiliations Department of Medical Microbiology and Infectious Diseases, College of Medicine, Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada, Molecular PathoBiology, National Microbiology Laboratory, Canadian Science Centre for Human and Animal Health, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
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Kamilla K. Gale,

Affiliation Molecular PathoBiology, National Microbiology Laboratory, Canadian Science Centre for Human and Animal Health, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
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Yulian Niu,

Affiliation Molecular PathoBiology, National Microbiology Laboratory, Canadian Science Centre for Human and Animal Health, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
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Clark S. Phillipson,

Affiliation Molecular PathoBiology, National Microbiology Laboratory, Canadian Science Centre for Human and Animal Health, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
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Timothy F. Booth,

Affiliations Department of Medical Microbiology and Infectious Diseases, College of Medicine, Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada, Viral Diseases, National Microbiology Laboratory, Canadian Science Centre for Human and Animal Health, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
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Stephanie A. Booth

* E-mail: Stephanie.Booth@phac-aspc.gc.ca

Affiliations Department of Medical Microbiology and Infectious Diseases, College of Medicine, Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada, Molecular PathoBiology, National Microbiology Laboratory, Canadian Science Centre for Human and Animal Health, Public Health Agency of Canada, Winnipeg, Manitoba, Canada

http://orcid.org/0000-0001-8108-5955

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Induction of Multiple miR-200/182 Members in the Brains of Mice Are Associated with Acute Herpes Simplex Virus 1 Encephalitis

Anna Majer,
Kyle A. Caligiuri,
Kamilla K. Gale,
Yulian Niu,
Clark S. Phillipson,
Timothy F. Booth,
Stephanie A. Booth

Published: January 3, 2017
https://doi.org/10.1371/journal.pone.0169081

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MicroRNAs
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Gene expression
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Brain damage
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Mouse models
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Encephalitis
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Herpes simplex virus-1
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RNA sequencing
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Immunohistochemistry techniques
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