A 2D-QSAR and Grid-Independent Molecular Descriptor (GRIND) Analysis of Quinoline-Type Inhibitors of Akt2: Exploration of the Binding Mode in the Pleckstrin Homology (PH) Domain

Open Access

Peer-reviewed

Research Article

Noreen Akhtar,

Affiliation Research Centre for Modeling and Simulation (RCMS), National University of Sciences and Technology (NUST), Islamabad, Pakistan
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Ishrat Jabeen

* E-mail: ishrat.jabeen@rcms.nust.edu.pk

Affiliation Research Centre for Modeling and Simulation (RCMS), National University of Sciences and Technology (NUST), Islamabad, Pakistan
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Hydrogen bonding
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Quinolines
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Binding analysis
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Breast cancer
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Crystal structure
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Drug interactions
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Lung and intrathoracic tumors
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