Colistin Dosage without Loading Dose Is Efficacious when Treating Carbapenem-Resistant Acinetobacter baumannii Ventilator-Associated Pneumonia Caused by Strains with High Susceptibility to Colistin

Rocío Álvarez-Marín; Rafael López-Rojas; Juan Antonio Márquez; María José Gómez; José Molina; José Miguel Cisneros; Carlos Ortiz-Leyba; Javier Aznar; José Garnacho-Montero; Jerónimo Pachón

doi:10.1371/journal.pone.0168468

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Peer-reviewed

Research Article

Colistin Dosage without Loading Dose Is Efficacious when Treating Carbapenem-Resistant Acinetobacter baumannii Ventilator-Associated Pneumonia Caused by Strains with High Susceptibility to Colistin

Rocío Álvarez-Marín ,

* E-mail: rocioalma@gmail.com (RAM); pachon@us.es (JP)

Affiliation Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine Infectious Diseases Research Group Institute of Biomedicine of Seville (IBiS) University of Seville/CSIC/University Hospitals Virgen del Rocio and Virgen Macarena, Seville, Spain

http://orcid.org/0000-0002-7101-2514

⨯
Rafael López-Rojas,

Affiliation Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine Infectious Diseases Research Group Institute of Biomedicine of Seville (IBiS) University of Seville/CSIC/University Hospitals Virgen del Rocio and Virgen Macarena, Seville, Spain
⨯
Juan Antonio Márquez,

Affiliation Clinical Unit of Critical Care and Emergencies, Institute of Biomedicine of Seville (IBiS), University Hospital Virgen del Rocío/CSIC/University of Seville, Seville, Spain
⨯
María José Gómez,

Affiliation Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine Infectious Diseases Research Group Institute of Biomedicine of Seville (IBiS) University of Seville/CSIC/University Hospitals Virgen del Rocio and Virgen Macarena, Seville, Spain
⨯
José Molina,

Affiliation Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine Infectious Diseases Research Group Institute of Biomedicine of Seville (IBiS) University of Seville/CSIC/University Hospitals Virgen del Rocio and Virgen Macarena, Seville, Spain
⨯
José Miguel Cisneros,

Affiliation Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine Infectious Diseases Research Group Institute of Biomedicine of Seville (IBiS) University of Seville/CSIC/University Hospitals Virgen del Rocio and Virgen Macarena, Seville, Spain
⨯
Carlos Ortiz-Leyba,

Affiliation Clinical Unit of Critical Care and Emergencies, Institute of Biomedicine of Seville (IBiS), University Hospital Virgen del Rocío/CSIC/University of Seville, Seville, Spain
⨯
Javier Aznar,

Affiliation Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine Infectious Diseases Research Group Institute of Biomedicine of Seville (IBiS) University of Seville/CSIC/University Hospitals Virgen del Rocio and Virgen Macarena, Seville, Spain
⨯
José Garnacho-Montero,

Affiliation Clinical Unit of Critical Care, University Hospital Virgen Macarena, Seville, Spain
⨯
Jerónimo Pachón

* E-mail: rocioalma@gmail.com (RAM); pachon@us.es (JP)

Affiliation Clinical Unit of Infectious Diseases, Microbiology and Preventive Medicine Infectious Diseases Research Group Institute of Biomedicine of Seville (IBiS) University of Seville/CSIC/University Hospitals Virgen del Rocio and Virgen Macarena, Seville, Spain
⨯

Colistin Dosage without Loading Dose Is Efficacious when Treating Carbapenem-Resistant Acinetobacter baumannii Ventilator-Associated Pneumonia Caused by Strains with High Susceptibility to Colistin

Rocío Álvarez-Marín,
Rafael López-Rojas,
Juan Antonio Márquez,
María José Gómez,
José Molina,
José Miguel Cisneros,
Carlos Ortiz-Leyba,
Javier Aznar,
José Garnacho-Montero,
Jerónimo Pachón

Published: December 19, 2016
https://doi.org/10.1371/journal.pone.0168468

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