Activated p53 with Histone Deacetylase Inhibitor Enhances L-Fucose-Mediated Drug Delivery through Induction of Fucosyltransferase 8 Expression in Hepatocellular Carcinoma Cells

Yutaka Okagawa; Kohichi Takada; Yohei Arihara; Shohei Kikuchi; Takahiro Osuga; Hajime Nakamura; Yusuke Kamihara; Naotaka Hayasaka; Makoto Usami; Kazuyuki Murase; Koji Miyanishi; Masayoshi Kobune; Junji Kato

doi:10.1371/journal.pone.0168355

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Research Article

Activated p53 with Histone Deacetylase Inhibitor Enhances L-Fucose-Mediated Drug Delivery through Induction of Fucosyltransferase 8 Expression in Hepatocellular Carcinoma Cells

Yutaka Okagawa ,

Contributed equally to this work with: Yutaka Okagawa, Kohichi Takada

Affiliation Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Kohichi Takada ,

Contributed equally to this work with: Yutaka Okagawa, Kohichi Takada

Affiliation Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Yohei Arihara,

Affiliation Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Shohei Kikuchi,

Affiliation Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Takahiro Osuga,

Affiliation Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Hajime Nakamura,

Affiliation Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Yusuke Kamihara,

Affiliation Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Naotaka Hayasaka,

Affiliation Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Makoto Usami,

Affiliation Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Kazuyuki Murase,

Affiliation Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Koji Miyanishi,

Affiliation Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Masayoshi Kobune,

Affiliation Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Junji Kato

* E-mail: jkato@sapmed.ac.jp

Affiliation Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯

Activated p53 with Histone Deacetylase Inhibitor Enhances L-Fucose-Mediated Drug Delivery through Induction of Fucosyltransferase 8 Expression in Hepatocellular Carcinoma Cells

Yutaka Okagawa,
Kohichi Takada,
Yohei Arihara,
Shohei Kikuchi,
Takahiro Osuga,
Hajime Nakamura,
Yusuke Kamihara,
Naotaka Hayasaka,
Makoto Usami,
Kazuyuki Murase

Published: December 15, 2016
https://doi.org/10.1371/journal.pone.0168355

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24 Oct 2018
06:20 GMT
Most Recent

How FUT8 expression is regulated Posted by Tsuchida on 24 Oct 2018 at 06:20 GMT

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