Knockdown of CREB3/Luman by shRNA in Mouse Granulosa Cells Results in Decreased Estradiol and Progesterone Synthesis and Promotes Cell Proliferation

Fan Zhao; Nan Wang; Yanglei Yi; Pengfei Lin; Keqiong Tang; Aihua Wang; Yaping Jin

doi:10.1371/journal.pone.0168246

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Peer-reviewed

Research Article

Knockdown of CREB3/Luman by shRNA in Mouse Granulosa Cells Results in Decreased Estradiol and Progesterone Synthesis and Promotes Cell Proliferation

Fan Zhao ,

Contributed equally to this work with: Fan Zhao, Nan Wang

Affiliations Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling, Shaanxi, China, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China
⨯
Nan Wang ,

Contributed equally to this work with: Fan Zhao, Nan Wang

Affiliations Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling, Shaanxi, China, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China
⨯
Yanglei Yi,

Affiliation College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China
⨯
Pengfei Lin,

Affiliations Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling, Shaanxi, China, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China
⨯
Keqiong Tang,

Affiliations Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling, Shaanxi, China, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China
⨯
Aihua Wang,

Affiliation College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China
⨯
Yaping Jin

* E-mail: yapingjin@163.com

Affiliations Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling, Shaanxi, China, College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China

http://orcid.org/0000-0001-5708-3159

⨯

Knockdown of CREB3/Luman by shRNA in Mouse Granulosa Cells Results in Decreased Estradiol and Progesterone Synthesis and Promotes Cell Proliferation

Fan Zhao,
Nan Wang,
Yanglei Yi,
Pengfei Lin,
Keqiong Tang,
Aihua Wang,
Yaping Jin

Published: December 14, 2016
https://doi.org/10.1371/journal.pone.0168246

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