Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner

• Hui Chen Su,

  Affiliation Department of Pharmacy, Chi-Mei Medical Center, Tainan, Taiwan

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• Yan A. Liang,

  Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America

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• Ying-Jung J. Lai,

  Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America

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• Yi-Lin Chiu,

  Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America

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• Robert B. Barndt,

  Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America

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• Frank Shiao,

  Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America

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• Hsiang-Hua D. Chang,

  Affiliations Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America, Department of Biochemistry, National Defense Medical Center, Taipei, Taiwan

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• Dajun D. Lu,

  Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America

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• Nanxi Huang,

  Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America

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• Chun-Che Tseng,

  Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America

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• Jehng-Kang Wang,

  Affiliation Department of Biochemistry, National Defense Medical Center, Taipei, Taiwan

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• Ming-Shyue Lee,

  Affiliation Graduate Institute of Biochemistry and Molecular Biology, College of Medicine National Taiwan University, Taipei, Taiwan

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• Michael D. Johnson,

  Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America

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• Shih-Ming Huang ,

  * E-mail: lincy@georgetown.edu (CYL); shihming@mail.ndmctsgh.edu.tw (SMH)

  Affiliation Department of Biochemistry, National Defense Medical Center, Taipei, Taiwan

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• Chen-Yong Lin

  * E-mail: lincy@georgetown.edu (CYL); shihming@mail.ndmctsgh.edu.tw (SMH)

  Affiliation Lombardi Comprehensive Cancer Center, Department of Oncology Georgetown University, Washington DC, United States of America

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