Unsupervised Cryo-EM Data Clustering through Adaptively Constrained K-Means Algorithm

Open Access

Peer-reviewed

Research Article

Yaofang Xu,

Affiliation Department of Biophysics, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China
⨯
Jiayi Wu,

Affiliation State Key Laboratory of Artificial Microstructure and Mesoscopic Physics, Institute of Condensed Matter Physics, School of Physics, Center for Quantitative Biology, Peking University, Beijing, China
⨯
Chang-Cheng Yin ,

* E-mail: youdong_mao@dfci.harvard.edu (YM); ccyin@hsc.pku.edu.cn (CY)

Affiliation Department of Biophysics, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China
⨯
Youdong Mao

* E-mail: youdong_mao@dfci.harvard.edu (YM); ccyin@hsc.pku.edu.cn (CY)

Affiliations State Key Laboratory of Artificial Microstructure and Mesoscopic Physics, Institute of Condensed Matter Physics, School of Physics, Center for Quantitative Biology, Peking University, Beijing, China, Intel Parallel Computing Center for Structural Biology, Dana-Farber Cancer Institute, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, United States of America
⨯

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Electron cryo-microscopy
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Clustering algorithms
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Algorithms
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Cluster analysis
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Multiple alignment calculation
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Simulation and modeling
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Inflammasomes
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k means clustering
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