Non-Publication Is Common among Phase 1, Single-Center, Not Prospectively Registered, or Early Terminated Clinical Drug Trials

• Cornelis A. van den Bogert,

  Affiliations Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, TB Utrecht, The Netherlands, Central Committee on Research involving Human Subjects (CCMO), BH The Hague, the Netherlands, National Institute for Public Health and the Environment (RIVM), Division of Public Health and Health Services, BA Bilthoven, The Netherlands

  http://orcid.org/0000-0003-0588-5218

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• Patrick C. Souverein ,

  * E-mail: p.c.souverein@uu.nl

  Affiliation Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, TB Utrecht, The Netherlands

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• Cecile T. M. Brekelmans,

  Affiliation Central Committee on Research involving Human Subjects (CCMO), BH The Hague, the Netherlands

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• Susan W. J. Janssen,

  Affiliation National Institute for Public Health and the Environment (RIVM), Division of Public Health and Health Services, BA Bilthoven, The Netherlands

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• Gerard H. Koëter,

  Affiliation Central Committee on Research involving Human Subjects (CCMO), BH The Hague, the Netherlands

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• Hubert G. M. Leufkens,

  Affiliation Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, TB Utrecht, The Netherlands

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• Lex M. Bouter

  Affiliation VU University Medical Center, Department of Epidemiology and Biostatistics, MB Amsterdam, the Netherlands

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