Increased Natural Killer Cell Activation in HIV-Infected Immunologic Non-Responders Correlates with CD4+ T Cell Recovery after Antiretroviral Therapy and Viral Suppression

Zhenwu Luo; Zhen Li; Lisa Martin; Zhiliang Hu; Hao Wu; Zhuang Wan; Michael Kilby; Sonya L. Heath; Lei Huang; Wei Jiang

doi:10.1371/journal.pone.0167640

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Open Access

Peer-reviewed

Research Article

Increased Natural Killer Cell Activation in HIV-Infected Immunologic Non-Responders Correlates with CD4+ T Cell Recovery after Antiretroviral Therapy and Viral Suppression

Zhenwu Luo,

Affiliation Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, United States of America
⨯
Zhen Li,

Affiliations Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, United States of America, Beijing You’an Hospital, Capital Medical University, No.8 Xitoutiao, You’an men wai, Fengtai District, Beijing, China
⨯
Lisa Martin,

Affiliation Divison of Infectious Diseases, Department of Medicine, Medical University of South Carolina, Charleston, United States of America
⨯
Zhiliang Hu,

Affiliations Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, United States of America, Department of Infectious Disease, the Second Affiliated Hospital of the Southeast University, Nanjing, China
⨯
Hao Wu,

Affiliation Beijing You’an Hospital, Capital Medical University, No.8 Xitoutiao, You’an men wai, Fengtai District, Beijing, China
⨯
Zhuang Wan,

Affiliation Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, United States of America
⨯
Michael Kilby,

Affiliation Divison of Infectious Diseases, Department of Medicine, Medical University of South Carolina, Charleston, United States of America
⨯
Sonya L. Heath,

Affiliation Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States of America
⨯
Lei Huang ,

* E-mail: jianw@musc.edu (WJ); huangleiwa@sina.com (LH)

Affiliation The 302 Hospital of PLA, Treatment and Research Center for Infectious Diseases, Beijing, China
⨯
Wei Jiang

* E-mail: jianw@musc.edu (WJ); huangleiwa@sina.com (LH)

Affiliations Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, United States of America, Divison of Infectious Diseases, Department of Medicine, Medical University of South Carolina, Charleston, United States of America
⨯

Increased Natural Killer Cell Activation in HIV-Infected Immunologic Non-Responders Correlates with CD4+ T Cell Recovery after Antiretroviral Therapy and Viral Suppression

Zhenwu Luo,
Zhen Li,
Lisa Martin,
Zhiliang Hu,
Hao Wu,
Zhuang Wan,
Michael Kilby,
Sonya L. Heath,
Lei Huang,
Wei Jiang

Published: January 11, 2017
https://doi.org/10.1371/journal.pone.0167640

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