Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium

• Xu Tian ,

  Contributed equally to this work with: Xu Tian, Keyur Patel, John R. Ridpath

  Affiliation Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

  http://orcid.org/0000-0001-8174-5669

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• Keyur Patel ,

  Contributed equally to this work with: Xu Tian, Keyur Patel, John R. Ridpath

  Affiliation Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

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• John R. Ridpath ,

  Contributed equally to this work with: Xu Tian, Keyur Patel, John R. Ridpath

  Affiliation Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

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• Youjun Chen,

  Affiliation Department of Neurology, UNC Neuroscience center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

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• Yi-Hui Zhou,

  Affiliations Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina

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• Dayna Neo,

  Affiliation Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

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• Jean Clement,

  Affiliation Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

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• Minoru Takata,

  Affiliation Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Kyoto University, Kyoto, Japan

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• Shunichi Takeda,

  Affiliation Department of Radiation Genetics Graduate School of Medicine, Kyoto University, Kyoto, Japan

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• Julian Sale,

  Affiliation Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom

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• Fred A. Wright ,

  * E-mail: ynakamur@email.unc.edu (JN); fred_wright@ncsu.edu (FW)

  Affiliations Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, Department of Statistics, North Carolina State University, Raleigh, North Carolina

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• James A. Swenberg,

  Affiliations Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, Curriculum in Toxicology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

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• Jun Nakamura

  * E-mail: ynakamur@email.unc.edu (JN); fred_wright@ncsu.edu (FW)

  Affiliation Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

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