Decreased Functional Connectivity of Insular Cortex in Drug Naïve First Episode Schizophrenia: In Relation to Symptom Severity

Lijuan Pang; David Kennedy; Qinling Wei; Luxian Lv; Jinsong Gao; Hong Li; Meina Quan; Xue Li; Yongfeng Yang; Xiaoduo Fan; Xueqin Song

doi:10.1371/journal.pone.0167242

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Peer-reviewed

Research Article

Decreased Functional Connectivity of Insular Cortex in Drug Naïve First Episode Schizophrenia: In Relation to Symptom Severity

Lijuan Pang ,

¶‡ These authors share co-first authorship on this work.

Affiliation The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
⨯
David Kennedy ,

¶‡ These authors share co-first authorship on this work.

Affiliation Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Qinling Wei ,

¶‡ These authors share co-first authorship on this work.

Affiliation Department of Psychiatry, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
⨯
Luxian Lv,

Affiliations Henan Province Biological Psychiatry Key Laboratory, Xinxiang Medical University, Xinxiang, China, Henan Province Mental Hospital, the Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, China
⨯
Jinsong Gao,

Affiliation The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
⨯
Hong Li,

Affiliation The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
⨯
Meina Quan,

Affiliation Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Xue Li,

Affiliation The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
⨯
Yongfeng Yang,

Affiliations Henan Province Biological Psychiatry Key Laboratory, Xinxiang Medical University, Xinxiang, China, Henan Province Mental Hospital, the Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, China
⨯
Xiaoduo Fan,

Affiliation Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Xueqin Song

* E-mail: sxqzhll@126.com

Affiliation The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
⨯

Decreased Functional Connectivity of Insular Cortex in Drug Naïve First Episode Schizophrenia: In Relation to Symptom Severity

Lijuan Pang,
David Kennedy,
Qinling Wei,
Luxian Lv,
Jinsong Gao,
Hong Li,
Meina Quan,
Xue Li,
Yongfeng Yang,
Xiaoduo Fan

Published: January 20, 2017
https://doi.org/10.1371/journal.pone.0167242

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