Antiviral Efficacy of Verdinexor In Vivo in Two Animal Models of Influenza A Virus Infection

Olivia Perwitasari; Scott Johnson; Xiuzhen Yan; Emery Register; Jackelyn Crabtree; Jon Gabbard; Elizabeth Howerth; Sharon Shacham; Robert Carlson; Sharon Tamir; Ralph A. Tripp

doi:10.1371/journal.pone.0167221

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Peer-reviewed

Research Article

Antiviral Efficacy of Verdinexor In Vivo in Two Animal Models of Influenza A Virus Infection

Olivia Perwitasari,

Affiliation Department of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, Georgia, United States of America
⨯
Scott Johnson,

Affiliation Department of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, Georgia, United States of America
⨯
Xiuzhen Yan,

Affiliation Department of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, Georgia, United States of America
⨯
Emery Register,

Affiliation Department of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, Georgia, United States of America
⨯
Jackelyn Crabtree,

Affiliation Department of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, Georgia, United States of America
⨯
Jon Gabbard,

Current address: University of Louisville Center for Predictive Medicine, Louisville, Kentucky

Affiliation Department of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, Georgia, United States of America
⨯
Elizabeth Howerth,

Affiliation Department of Pathology, University of Georgia College of Veterinary Medicine, Athens, Georgia, United States of America
⨯
Sharon Shacham,

Affiliation Karyopharm Therapeutics, Newton, Massachusetts, United States of America
⨯
Robert Carlson,

Affiliation Karyopharm Therapeutics, Newton, Massachusetts, United States of America
⨯
Sharon Tamir,

Affiliation Karyopharm Therapeutics, Newton, Massachusetts, United States of America
⨯
Ralph A. Tripp

* E-mail: ratripp@uga.edu

Affiliation Department of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, Georgia, United States of America
⨯

Antiviral Efficacy of Verdinexor In Vivo in Two Animal Models of Influenza A Virus Infection

Olivia Perwitasari,
Scott Johnson,
Xiuzhen Yan,
Emery Register,
Jackelyn Crabtree,
Jon Gabbard,
Elizabeth Howerth,
Sharon Shacham,
Robert Carlson,
Sharon Tamir

Published: November 28, 2016
https://doi.org/10.1371/journal.pone.0167221

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