Time-Dependent Regulation of IL-2R α-Chain (CD25) Expression by TCR Signal Strength and IL-2-Induced STAT5 Signaling in Activated Human Blood T Lymphocytes

Open Access

Peer-reviewed

Research Article

Alla N. Shatrova,

Affiliation Department of Intracellular Signaling and Transport, Institute of Cytology, Russian Academy of Sciences, St-Petersburg, Russia
⨯
Elena V. Mityushova,

Affiliation Department of Intracellular Signaling and Transport, Institute of Cytology, Russian Academy of Sciences, St-Petersburg, Russia
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Irina O. Vassilieva,

Affiliation Department of Intracellular Signaling and Transport, Institute of Cytology, Russian Academy of Sciences, St-Petersburg, Russia
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Nikolay D. Aksenov,

Affiliation Department of Intracellular Signaling and Transport, Institute of Cytology, Russian Academy of Sciences, St-Petersburg, Russia
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Valery V. Zenin,

Affiliation Department of Intracellular Signaling and Transport, Institute of Cytology, Russian Academy of Sciences, St-Petersburg, Russia
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Nikolay N. Nikolsky,

Affiliation Department of Intracellular Signaling and Transport, Institute of Cytology, Russian Academy of Sciences, St-Petersburg, Russia
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Irina I. Marakhova

* E-mail: iim@incras.ru

Affiliation Department of Intracellular Signaling and Transport, Institute of Cytology, Russian Academy of Sciences, St-Petersburg, Russia
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T cells
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STAT signaling
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TCR signaling cascade
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Phosphorylation
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Blood
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Gene regulation
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Gene expression
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Tyrosine kinases
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