The Role of DNA Methylation and Histone Modifications in Neurodegenerative Diseases: A Systematic Review

Ke-xin Wen; Jelena Miliç; Bassem El-Khodor; Klodian Dhana; Jana Nano; Tammy Pulido; Bledar Kraja; Asija Zaciragic; Wichor M. Bramer; John Troup; Rajiv Chowdhury; M. Arfam Ikram; Abbas Dehghan; Taulant Muka; Oscar H. Franco

doi:10.1371/journal.pone.0167201

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Open Access

Peer-reviewed

Research Article

The Role of DNA Methylation and Histone Modifications in Neurodegenerative Diseases: A Systematic Review

Ke-xin Wen ,

Contributed equally to this work with: Ke-xin Wen, Jelena Miliç

* E-mail: k.wen@erasmusmc.nl (KW); t.muka@erasmusmc.nl (TM)

Affiliation Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands
⨯
Jelena Miliç ,

Contributed equally to this work with: Ke-xin Wen, Jelena Miliç

Affiliation Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands
⨯
Bassem El-Khodor,

Affiliation Research and Development, Metagenics, Inc, United States of America
⨯
Klodian Dhana,

Affiliation Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands
⨯
Jana Nano,

Affiliation Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands
⨯
Tammy Pulido,

Affiliation Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands
⨯
Bledar Kraja,

Affiliations Department of Biomedical Sciences, Faculty of Medicine, University of Medicine, Tirana, Albania, University Clinic of Gastrohepatology, University Hospital Center Mother Teresa, Tirana, Albania
⨯
Asija Zaciragic,

Affiliation Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands
⨯
Wichor M. Bramer,

Affiliation Medical Library, Erasmus MC, Rotterdam, The Netherlands
⨯
John Troup,

Affiliation Research and Development, Metagenics, Inc, United States of America
⨯
Rajiv Chowdhury,

Affiliation Department of Public Health & Primary Care, Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB1 8RN, United Kingdom
⨯
M. Arfam Ikram,

Affiliation Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands
⨯
Abbas Dehghan,

Affiliation Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands
⨯
Taulant Muka ,

* E-mail: k.wen@erasmusmc.nl (KW); t.muka@erasmusmc.nl (TM)

Affiliation Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands
⨯
Oscar H. Franco

Affiliation Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands
⨯

The Role of DNA Methylation and Histone Modifications in Neurodegenerative Diseases: A Systematic Review

Ke-xin Wen,
Jelena Miliç,
Bassem El-Khodor,
Klodian Dhana,
Jana Nano,
Tammy Pulido,
Bledar Kraja,
Asija Zaciragic,
Wichor M. Bramer,
John Troup

Published: December 14, 2016
https://doi.org/10.1371/journal.pone.0167201

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DNA methylation
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Alzheimer's disease
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