The Role of Reactive Oxygen Species in β-Adrenergic Signaling in Cardiomyocytes from Mice with the Metabolic Syndrome

Monica Llano-Diez; Jon Sinclair; Takashi Yamada; Mei Zong; Jeremy Fauconnier; Shi-Jin Zhang; Abram Katz; Kent Jardemark; Håkan Westerblad; Daniel C. Andersson; Johanna T. Lanner

doi:10.1371/journal.pone.0167090

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Open Access

Peer-reviewed

Research Article

The Role of Reactive Oxygen Species in β-Adrenergic Signaling in Cardiomyocytes from Mice with the Metabolic Syndrome

Monica Llano-Diez,

Affiliation Karolinska Institutet, Department of Physiology & Pharmacology, Stockholm, Sweden
⨯
Jon Sinclair,

Affiliation Karolinska Institutet, Department of Physiology & Pharmacology, Stockholm, Sweden
⨯
Takashi Yamada,

Current address: Sapporo Medical University, Graduate School of Health Sciences, Sapporo, Japan

Affiliation Karolinska Institutet, Department of Physiology & Pharmacology, Stockholm, Sweden
⨯
Mei Zong,

Affiliation Karolinska University Hospital, Rheumatology unit, CMM, Stockholm Sweden
⨯
Jeremy Fauconnier,

Current address: University of Montpellier, U1046 INSERM, Montpellier, France

Affiliation Karolinska Institutet, Department of Physiology & Pharmacology, Stockholm, Sweden
⨯
Shi-Jin Zhang,

Affiliation Karolinska Institutet, Department of Physiology & Pharmacology, Stockholm, Sweden
⨯
Abram Katz,

Current address: Ariel University, Department of Physical Therapy, School of Health Sciences, Ariel, Israel

Affiliation Karolinska Institutet, Department of Physiology & Pharmacology, Stockholm, Sweden
⨯
Kent Jardemark,

Affiliation Karolinska Institutet, Department of Physiology & Pharmacology, Stockholm, Sweden
⨯
Håkan Westerblad,

Affiliation Karolinska Institutet, Department of Physiology & Pharmacology, Stockholm, Sweden
⨯
Daniel C. Andersson,

Affiliation Karolinska Institutet, Department of Medicine, Stockholm, Sweden
⨯
Johanna T. Lanner

* E-mail: Johanna.Lanner@ki.se

Affiliation Karolinska Institutet, Department of Physiology & Pharmacology, Stockholm, Sweden

http://orcid.org/0000-0002-1222-9473

⨯

The Role of Reactive Oxygen Species in β-Adrenergic Signaling in Cardiomyocytes from Mice with the Metabolic Syndrome

Monica Llano-Diez,
Jon Sinclair,
Takashi Yamada,
Mei Zong,
Jeremy Fauconnier,
Shi-Jin Zhang,
Abram Katz,
Kent Jardemark,
Håkan Westerblad,
Daniel C. Andersson

Published: December 1, 2016
https://doi.org/10.1371/journal.pone.0167090

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Cardiomyocytes
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Mitochondria
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Metabolic syndrome
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Heart
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Mouse models
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Redox signaling
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