Determination of a Screening Metric for High Diversity DNA Libraries

Open Access

Peer-reviewed

Research Article

Nicholas J. Guido ,

Contributed equally to this work with: Nicholas J. Guido, Steven Handerson

* E-mail: nguido@gen9bio.com

Affiliation Gen9 Inc., Cambridge, Massachusetts, United States of America
⨯
Steven Handerson ,

Contributed equally to this work with: Nicholas J. Guido, Steven Handerson

Affiliation Gen9 Inc., Cambridge, Massachusetts, United States of America
⨯
Elaine M. Joseph,

Affiliation Gen9 Inc., Cambridge, Massachusetts, United States of America
⨯
Devin Leake,

Affiliation Gen9 Inc., Cambridge, Massachusetts, United States of America
⨯
Li A. Kung

Affiliation Gen9 Inc., Cambridge, Massachusetts, United States of America
⨯

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Library screening
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Sequence alignment
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DNA libraries
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Next-generation sequencing
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Nucleotide sequencing
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Probability distribution
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Numerical integration
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Screening guidelines
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