PTH1R Mutants Found in Patients with Primary Failure of Tooth Eruption Disrupt G-Protein Signaling

• Hariharan Subramanian ,

  Contributed equally to this work with: Hariharan Subramanian, Frank Döring

  Affiliations Institute of Clinical Biochemistry and Pathobiochemistry, University of Wuerzburg, Wuerzburg, Germany, Institute of Experimental Cardiovascular Research, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany

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• Frank Döring ,

  Contributed equally to this work with: Hariharan Subramanian, Frank Döring

  Affiliation Institute of Physiology, AG Molecular Electrophysiology, University of Wuerzburg, Wuerzburg, Germany

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• Sina Kollert,

  Affiliation Institute of Physiology, AG Molecular Electrophysiology, University of Wuerzburg, Wuerzburg, Germany

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• Natalia Rukoyatkina,

  Affiliations Institute of Clinical Biochemistry and Pathobiochemistry, University of Wuerzburg, Wuerzburg, Germany, Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia

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• Julia Sturm,

  Affiliation Institute of Physiology, AG Molecular Electrophysiology, University of Wuerzburg, Wuerzburg, Germany

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• Stepan Gambaryan,

  Affiliations Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia, Department of Cytology and Histology, St. Petersburg State University, St. Petersburg Russia

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• Angelika Stellzig-Eisenhauer,

  Affiliation Department of Orthodontics, University Clinic of Wuerzburg, Wuerzburg, Germany

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• Philipp Meyer-Marcotty,

  Affiliations Department of Orthodontics, University Clinic of Wuerzburg, Wuerzburg, Germany, Department of Orthodontics, University Clinic of Goettingen, Goettingen, Germany

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• Martin Eigenthaler ,

  * E-mail: M.Eigenthaler@medizin.uni-wuerzburg.de

  ¶‡ These authors are joint senior authors on this work.

  Affiliations Institute of Clinical Biochemistry and Pathobiochemistry, University of Wuerzburg, Wuerzburg, Germany, Department of Orthodontics, University Clinic of Wuerzburg, Wuerzburg, Germany

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• Erhard Wischmeyer

  ¶‡ These authors are joint senior authors on this work.

  Affiliation Institute of Physiology, AG Molecular Electrophysiology, University of Wuerzburg, Wuerzburg, Germany

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