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Open Access

Peer-reviewed

Research Article

Equol Attenuates Atherosclerosis in Apolipoprotein E-Deficient Mice by Inhibiting Endoplasmic Reticulum Stress via Activation of Nrf2 in Endothelial Cells

Ting Zhang ,

Contributed equally to this work with: Ting Zhang, Qin Hu

Affiliation Research Center of Nutrition and Food Safety, Institute of Military Preventive Medicine, Third Military Medical University, Chongqing Key Laboratory of Nutrition and Food Safety, Chongqing, P. R.China
⨯
Qin Hu ,

Contributed equally to this work with: Ting Zhang, Qin Hu

Affiliation Research Center of Nutrition and Food Safety, Institute of Military Preventive Medicine, Third Military Medical University, Chongqing Key Laboratory of Nutrition and Food Safety, Chongqing, P. R.China
⨯
Linying Shi,

Affiliation Research Center of Nutrition and Food Safety, Institute of Military Preventive Medicine, Third Military Medical University, Chongqing Key Laboratory of Nutrition and Food Safety, Chongqing, P. R.China
⨯
Li Qin,

Affiliation Research Center of Nutrition and Food Safety, Institute of Military Preventive Medicine, Third Military Medical University, Chongqing Key Laboratory of Nutrition and Food Safety, Chongqing, P. R.China
⨯
Qianyong Zhang ,

* E-mail: mantianmi@hotmail.com (MM); 248141998@qq.com (QZ)

Affiliation Research Center of Nutrition and Food Safety, Institute of Military Preventive Medicine, Third Military Medical University, Chongqing Key Laboratory of Nutrition and Food Safety, Chongqing, P. R.China
⨯
Mantian Mi

* E-mail: mantianmi@hotmail.com (MM); 248141998@qq.com (QZ)

Affiliation Research Center of Nutrition and Food Safety, Institute of Military Preventive Medicine, Third Military Medical University, Chongqing Key Laboratory of Nutrition and Food Safety, Chongqing, P. R.China
⨯

Equol Attenuates Atherosclerosis in Apolipoprotein E-Deficient Mice by Inhibiting Endoplasmic Reticulum Stress via Activation of Nrf2 in Endothelial Cells

Ting Zhang,
Qin Hu,
Linying Shi,
Li Qin,
Qianyong Zhang,
Mantian Mi

x

Published: December 1, 2016
https://doi.org/10.1371/journal.pone.0167020

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Apoptosis
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Atherosclerosis
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Aorta
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Small interfering RNA
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Stress signaling cascade
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Endoplasmic reticulum
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Endothelial cells
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Transcription factors
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