Chidamide Inhibits Aerobic Metabolism to Induce Pancreatic Cancer Cell Growth Arrest by Promoting Mcl-1 Degradation

Mu He; Zhixin Qiao; Yanbing Wang; Qiyuan Kuai; Changlan Li; Yu Wang; Xingwei Jiang; Xuanlin Wang; Weijing Li; Min He; Suping Ren; Qun Yu

doi:10.1371/journal.pone.0166896

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Open Access

Peer-reviewed

Research Article

Chidamide Inhibits Aerobic Metabolism to Induce Pancreatic Cancer Cell Growth Arrest by Promoting Mcl-1 Degradation

Mu He ,

Contributed equally to this work with: Mu He, Zhixin Qiao

Affiliations Department of Blood Products and Substitutes, Beijing Institute of Transfusion Medicine, Beijing, China, Microbiology Laboratory, Shunyi District Center for Disease Control and Prevention, Beijing, China
⨯
Zhixin Qiao ,

Contributed equally to this work with: Mu He, Zhixin Qiao

Affiliation Medical Research Centre, Beijing Tongren Hospital, Capital Medical University, Beijing, China
⨯
Yanbing Wang,

Affiliation Department of Blood Products and Substitutes, Beijing Institute of Transfusion Medicine, Beijing, China
⨯
Qiyuan Kuai,

Affiliation Department of Blood Products and Substitutes, Beijing Institute of Transfusion Medicine, Beijing, China
⨯
Changlan Li,

Affiliation Department of Blood Products and Substitutes, Beijing Institute of Transfusion Medicine, Beijing, China
⨯
Yu Wang,

Affiliation Department of Blood Products and Substitutes, Beijing Institute of Transfusion Medicine, Beijing, China
⨯
Xingwei Jiang,

Affiliation Department of Blood Products and Substitutes, Beijing Institute of Transfusion Medicine, Beijing, China
⨯
Xuanlin Wang,

Affiliation Department of Blood Products and Substitutes, Beijing Institute of Transfusion Medicine, Beijing, China
⨯
Weijing Li,

Affiliation Department of Blood Products and Substitutes, Beijing Institute of Transfusion Medicine, Beijing, China
⨯
Min He,

Affiliation Department of Blood Products and Substitutes, Beijing Institute of Transfusion Medicine, Beijing, China
⨯
Suping Ren ,

* E-mail: yuqun1970@outlook.com (QY); rensp12@yahoo.com (SR)

Affiliation Department of Blood Products and Substitutes, Beijing Institute of Transfusion Medicine, Beijing, China
⨯
Qun Yu

* E-mail: yuqun1970@outlook.com (QY); rensp12@yahoo.com (SR)

Affiliation Department of Blood Products and Substitutes, Beijing Institute of Transfusion Medicine, Beijing, China
⨯

Chidamide Inhibits Aerobic Metabolism to Induce Pancreatic Cancer Cell Growth Arrest by Promoting Mcl-1 Degradation

Mu He,
Zhixin Qiao,
Yanbing Wang,
Qiyuan Kuai,
Changlan Li,
Yu Wang,
Xingwei Jiang,
Xuanlin Wang,
Weijing Li,
Min He

Published: November 22, 2016
https://doi.org/10.1371/journal.pone.0166896

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