Caspase-Dependent and Caspase-Independent Pathways Are Involved in Cadmium-Induced Apoptosis in Primary Rat Proximal Tubular Cell Culture

Gang Liu; Hui Zou; Tongwang Luo; Mengfei Long; Jianchun Bian; Xuezhong Liu; Jianhong Gu; Yan Yuan; Ruilong Song; Yi Wang; Jiaqiao Zhu; Zongping Liu

doi:10.1371/journal.pone.0166823

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Open Access

Peer-reviewed

Research Article

Caspase-Dependent and Caspase-Independent Pathways Are Involved in Cadmium-Induced Apoptosis in Primary Rat Proximal Tubular Cell Culture

Gang Liu ,

Contributed equally to this work with: Gang Liu, Hui Zou, Tongwang Luo

Affiliation College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, and Jiangsu Key Laboratory of Zoonosis, Yangzhou, Jiangsu, PR China
⨯
Hui Zou ,

Contributed equally to this work with: Gang Liu, Hui Zou, Tongwang Luo

Affiliation College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, and Jiangsu Key Laboratory of Zoonosis, Yangzhou, Jiangsu, PR China
⨯
Tongwang Luo ,

Contributed equally to this work with: Gang Liu, Hui Zou, Tongwang Luo

Affiliation College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, and Jiangsu Key Laboratory of Zoonosis, Yangzhou, Jiangsu, PR China
⨯
Mengfei Long,

Affiliation College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, and Jiangsu Key Laboratory of Zoonosis, Yangzhou, Jiangsu, PR China
⨯
Jianchun Bian,

Affiliation College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, and Jiangsu Key Laboratory of Zoonosis, Yangzhou, Jiangsu, PR China
⨯
Xuezhong Liu,

Affiliation College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, and Jiangsu Key Laboratory of Zoonosis, Yangzhou, Jiangsu, PR China
⨯
Jianhong Gu,

Affiliation College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, and Jiangsu Key Laboratory of Zoonosis, Yangzhou, Jiangsu, PR China
⨯
Yan Yuan,

Affiliation College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, and Jiangsu Key Laboratory of Zoonosis, Yangzhou, Jiangsu, PR China
⨯
Ruilong Song,

Affiliation College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, and Jiangsu Key Laboratory of Zoonosis, Yangzhou, Jiangsu, PR China
⨯
Yi Wang,

Affiliation College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, and Jiangsu Key Laboratory of Zoonosis, Yangzhou, Jiangsu, PR China
⨯
Jiaqiao Zhu ,

* E-mail: liuzongping@yzu.edu.cn (ZPL); jqzhu1998@163.com (JQZ)

Affiliation College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, and Jiangsu Key Laboratory of Zoonosis, Yangzhou, Jiangsu, PR China
⨯
Zongping Liu

* E-mail: liuzongping@yzu.edu.cn (ZPL); jqzhu1998@163.com (JQZ)

Affiliation College of Veterinary Medicine, Yangzhou University, and Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, and Jiangsu Key Laboratory of Zoonosis, Yangzhou, Jiangsu, PR China
⨯

Caspase-Dependent and Caspase-Independent Pathways Are Involved in Cadmium-Induced Apoptosis in Primary Rat Proximal Tubular Cell Culture

Gang Liu,
Hui Zou,
Tongwang Luo,
Mengfei Long,
Jianchun Bian,
Xuezhong Liu,
Jianhong Gu,
Yan Yuan,
Ruilong Song,
Yi Wang

Published: November 18, 2016
https://doi.org/10.1371/journal.pone.0166823

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