Isoflurane Exposure Induces Cell Death, Microglial Activation and Modifies the Expression of Genes Supporting Neurodevelopment and Cognitive Function in the Male Newborn Piglet Brain

• Kevin D. Broad ,

  Contributed equally to this work with: Kevin D. Broad, Jane Hassell

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Jane Hassell ,

  Contributed equally to this work with: Kevin D. Broad, Jane Hassell

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Bobbi Fleiss,

  Affiliations Centre for the Developing Brain, Kings College, St Thomas’s Campus, London, United Kingdom, Inserm, Paris, France, University Paris Diderot, Sorbonne Paris Cite, Paris, France

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• Go Kawano,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Mojgan Ezzati,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Eridan Rocha-Ferreira,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Mariya Hristova,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Kate Bennett,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Igor Fierens,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Ryan Burnett,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Badr Chaban,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Daniel Alonso-Alconada,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Aaron Oliver-Taylor,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Ilias Tachsidis,

  Affiliation Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom

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• Jamshid Rostami,

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

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• Pierre Gressens,

  Affiliations Centre for the Developing Brain, Kings College, St Thomas’s Campus, London, United Kingdom, Inserm, Paris, France, University Paris Diderot, Sorbonne Paris Cite, Paris, France

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• Robert D. Sanders,

  Affiliations Department of Anesthesiology, University of Wisconsin, Madison, United States of America, Wellcome Department of Imaging Neuroscience, University College London, London, United Kingdom, Surgical Outcomes Research Centre, University College London Hospital, London, United Kingdom

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•  [ ... ],
• Nicola J. Robertson

  * E-mail: n.robertson@ucl.ac.uk

  Affiliation Institute for Women’s Health, University College London, London, United Kingdom

  http://orcid.org/0000-0002-5783-0828

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