Tumor-Activated Mesenchymal Stromal Cells Promote Osteosarcoma Stemness and Migratory Potential via IL-6 Secretion

Open Access

Peer-reviewed

Research Article

Margherita Cortini,

Affiliations Orthopaedic Pathophysiology and Regenerative Medicine Unit, Istituto Ortopedico Rizzoli (IOR), 40136, Bologna, Italy, Department of Biomedical and Neuromotor Sciences, University of Bologna, 40126, Bologna, Italy
⨯
Annamaria Massa,

Affiliation Orthopaedic Pathophysiology and Regenerative Medicine Unit, Istituto Ortopedico Rizzoli (IOR), 40136, Bologna, Italy
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Sofia Avnet,

Affiliation Orthopaedic Pathophysiology and Regenerative Medicine Unit, Istituto Ortopedico Rizzoli (IOR), 40136, Bologna, Italy
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Gloria Bonuccelli,

Affiliation Orthopaedic Pathophysiology and Regenerative Medicine Unit, Istituto Ortopedico Rizzoli (IOR), 40136, Bologna, Italy
⨯
Nicola Baldini

* E-mail: nicola.baldini@ior.it

Affiliations Orthopaedic Pathophysiology and Regenerative Medicine Unit, Istituto Ortopedico Rizzoli (IOR), 40136, Bologna, Italy, Department of Biomedical and Neuromotor Sciences, University of Bologna, 40126, Bologna, Italy
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Mesenchymal stem cells
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Secretion
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Breast cancer
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Malignant tumors
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Cancer stem cells
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Stromal cells
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Cytokines
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Metastasis
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