Characterization of a Novel Dermal Fibrosis Model Induced by Areca Nut Extract that Mimics Oral Submucous Fibrosis

Min-Hsuan Chiang; Ping-Ho Chen; Yuk-Kwan Chen; Chia-Hsin Chen; Mei-Ling Ho; Yan-Hsiung Wang

doi:10.1371/journal.pone.0166454

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Peer-reviewed

Research Article

Characterization of a Novel Dermal Fibrosis Model Induced by Areca Nut Extract that Mimics Oral Submucous Fibrosis

Min-Hsuan Chiang,

Affiliations School of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China, Orthopaedic Research Center, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China
⨯
Ping-Ho Chen,

Affiliations School of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China, Institute of Biomedical Sciences, National Sun Yat-sen University, Kaohsiung, Taiwan, Republic of China, Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China, Center for Infectious Disease and Cancer Research (CICAR), Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China
⨯
Yuk-Kwan Chen,

Affiliations School of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China, Oral & Maxillofacial Imaging Center, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China, Division of Oral Pathology & Maxillofacial Radiology, Department of Dentistry, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, Republic of China
⨯
Chia-Hsin Chen,

Affiliations Orthopaedic Research Center, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China, Department of Physical Medicine and Rehabilitation, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China, Department of Physical Medicine and Rehabilitation, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China
⨯
Mei-Ling Ho,

Affiliations Orthopaedic Research Center, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China, Department of Physiology, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China
⨯
Yan-Hsiung Wang

* E-mail: yhwang@kmu.edu.tw

Affiliations School of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China, Orthopaedic Research Center, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China
⨯

Characterization of a Novel Dermal Fibrosis Model Induced by Areca Nut Extract that Mimics Oral Submucous Fibrosis

Min-Hsuan Chiang,
Ping-Ho Chen,
Yuk-Kwan Chen,
Chia-Hsin Chen,
Mei-Ling Ho,
Yan-Hsiung Wang

Published: November 16, 2016
https://doi.org/10.1371/journal.pone.0166454

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