An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition

• Brian Egan ,

  * E-mail: egan@activemotif.com (BE); patrick.trojer@constellationpharma.com (PT)

  Affiliation Active Motif Inc., Carlsbad, California, United States of America

  http://orcid.org/0000-0002-6354-6575

  ⨯
• Chih-Chi Yuan,

  Affiliation Constellation Pharmaceuticals Inc., Cambridge, Massachusetts, United States of America

  ⨯
• Madeleine Lisa Craske,

  Affiliation Active Motif Inc., Carlsbad, California, United States of America

  ⨯
• Paul Labhart,

  Affiliation Active Motif Inc., Carlsbad, California, United States of America

  ⨯
• Gulfem D. Guler,

  Affiliation Department of Molecular Oncology, Genentech Inc., South San Francisco, California, United States of America

  ⨯
• David Arnott,

  Affiliation Department of Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America

  ⨯
• Tobias M. Maile,

  Affiliation Department of Protein Chemistry, Genentech Inc., South San Francisco, California, United States of America

  ⨯
• Jennifer Busby,

  Affiliation Constellation Pharmaceuticals Inc., Cambridge, Massachusetts, United States of America

  ⨯
• Chisato Henry,

  Affiliation Active Motif Inc., Carlsbad, California, United States of America

  ⨯
• Theresa K. Kelly,

  Affiliation Active Motif Inc., Carlsbad, California, United States of America

  ⨯
• Charles A. Tindell,

  Affiliation Department of Molecular Oncology, Genentech Inc., South San Francisco, California, United States of America

  ⨯
• Suchit Jhunjhunwala,

  Affiliation Department of Bioinformatics, Genentech Inc., South San Francisco, California, United States of America

  ⨯
• Feng Zhao,

  Affiliation Constellation Pharmaceuticals Inc., Cambridge, Massachusetts, United States of America

  ⨯
• Charlie Hatton,

  Affiliation Constellation Pharmaceuticals Inc., Cambridge, Massachusetts, United States of America

  ⨯
• Barbara M. Bryant,

  Affiliation Constellation Pharmaceuticals Inc., Cambridge, Massachusetts, United States of America

  ⨯
• Marie Classon ,

  Contributed equally to this work with: Marie Classon, Patrick Trojer

  Affiliation Department of Molecular Oncology, Genentech Inc., South San Francisco, California, United States of America

  ⨯
•  [ ... ],
• Patrick Trojer

  Contributed equally to this work with: Marie Classon, Patrick Trojer

  * E-mail: egan@activemotif.com (BE); patrick.trojer@constellationpharma.com (PT)

  Affiliation Constellation Pharmaceuticals Inc., Cambridge, Massachusetts, United States of America

  ⨯
• [ view all ]
• [ view less ]