Comparative Binding Analysis of Dipeptidyl Peptidase IV (DPP-4) with Antidiabetic Drugs – An Ab Initio Fragment Molecular Orbital Study

• Sundaram Arulmozhiraja,

  Affiliations Department of Chemistry, Rikkyo University, 3-34-1 Nishi-Ikebukuro, Toshima-ku, Tokyo 171–8501, Japan, Research Center for Smart molecules, Rikkyo University, 3-34-1 Nishi-Ikebukuro, Toshima-ku, Tokyo 171–8501, Japan

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• Naoya Matsuo,

  Affiliation Department of Chemistry, Rikkyo University, 3-34-1 Nishi-Ikebukuro, Toshima-ku, Tokyo 171–8501, Japan

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• Erika Ishitsubo,

  Affiliation Department of Chemistry, Rikkyo University, 3-34-1 Nishi-Ikebukuro, Toshima-ku, Tokyo 171–8501, Japan

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• Seiji Okazaki,

  Affiliations Department of Chemistry, Rikkyo University, 3-34-1 Nishi-Ikebukuro, Toshima-ku, Tokyo 171–8501, Japan, Research Center for Smart molecules, Rikkyo University, 3-34-1 Nishi-Ikebukuro, Toshima-ku, Tokyo 171–8501, Japan

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• Hitoshi Shimano,

  Affiliations Department of Internal Medicine (Endocrinology and Metabolism), University of Tsukuba, Tsukuba 305–8575, Japan, AMED-CREST, Tokyo, Japan

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• Hiroaki Tokiwa

  * E-mail: tokiwa@rikkyo.ac.jp

  Affiliations Department of Chemistry, Rikkyo University, 3-34-1 Nishi-Ikebukuro, Toshima-ku, Tokyo 171–8501, Japan, Research Center for Smart molecules, Rikkyo University, 3-34-1 Nishi-Ikebukuro, Toshima-ku, Tokyo 171–8501, Japan, AMED-CREST, Tokyo, Japan

  http://orcid.org/0000-0002-3790-1799

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