Chronic Activation of Hepatic Nrf2 Has No Major Effect on Fatty Acid and Glucose Metabolism in Adult Mice

Sebastian Brachs; Angelika F. Winkel; James Polack; Hui Tang; Maria Brachs; Daniel Margerie; Bodo Brunner; Kerstin Jahn-Hofmann; Hartmut Ruetten; Joachim Spranger; Dieter Schmoll

doi:10.1371/journal.pone.0166110

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Open Access

Peer-reviewed

Research Article

Chronic Activation of Hepatic Nrf2 Has No Major Effect on Fatty Acid and Glucose Metabolism in Adult Mice

Sebastian Brachs,

Affiliations Department of Endocrinology, Diabetes and Nutrition, Center for Cardiovascular Research, Charité –University School of Medicine, Berlin, Germany, German Center for Cardiovascular Research, DZHK Partner site Berlin, Berlin, Germany

http://orcid.org/0000-0002-6336-3939

⨯
Angelika F. Winkel,

Affiliation Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, Germany
⨯
James Polack,

Affiliations Department of Endocrinology, Diabetes and Nutrition, Center for Cardiovascular Research, Charité –University School of Medicine, Berlin, Germany, German Center for Cardiovascular Research, DZHK Partner site Berlin, Berlin, Germany
⨯
Hui Tang,

Affiliations Department of Endocrinology, Diabetes and Nutrition, Center for Cardiovascular Research, Charité –University School of Medicine, Berlin, Germany, German Center for Cardiovascular Research, DZHK Partner site Berlin, Berlin, Germany
⨯
Maria Brachs,

Affiliations Department of Endocrinology, Diabetes and Nutrition, Center for Cardiovascular Research, Charité –University School of Medicine, Berlin, Germany, German Center for Cardiovascular Research, DZHK Partner site Berlin, Berlin, Germany
⨯
Daniel Margerie,

Affiliation Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, Germany
⨯
Bodo Brunner,

Affiliation Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, Germany
⨯
Kerstin Jahn-Hofmann,

Affiliation Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, Germany
⨯
Hartmut Ruetten,

Affiliation Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, Germany
⨯
Joachim Spranger ,

* E-mail: joachim.spranger@charite.de

Affiliations Department of Endocrinology, Diabetes and Nutrition, Center for Cardiovascular Research, Charité –University School of Medicine, Berlin, Germany, German Center for Cardiovascular Research, DZHK Partner site Berlin, Berlin, Germany
⨯
Dieter Schmoll

Affiliation Sanofi-Aventis Deutschland GmbH, Industriepark Hoechst, Frankfurt am Main, Germany
⨯

Chronic Activation of Hepatic Nrf2 Has No Major Effect on Fatty Acid and Glucose Metabolism in Adult Mice

Sebastian Brachs,
Angelika F. Winkel,
James Polack,
Hui Tang,
Maria Brachs,
Daniel Margerie,
Bodo Brunner,
Kerstin Jahn-Hofmann,
Hartmut Ruetten,
Joachim Spranger

Published: November 4, 2016
https://doi.org/10.1371/journal.pone.0166110

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