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Open Access
Peer-reviewed
Research Article
The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments
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Zsófia Kohajda,
Affiliation MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary
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Nikolett Farkas-Morvay,
Affiliation Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary
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Norbert Jost,
Affiliations MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary, Department of Pathophysiology, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania
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Norbert Nagy,
Affiliation MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary
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Amir Geramipour,
Affiliation Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary
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András Horváth,
Affiliations Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary, MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary
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Richárd S. Varga,
Affiliation Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary
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Tibor Hornyik,
Affiliation Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary
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Claudia Corici,
Affiliation Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary
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Károly Acsai,
Affiliation MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary
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Balázs Horváth,
Affiliation Department of Physiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
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János Prorok,
Affiliation Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary
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Balázs Ördög,
Affiliation Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary
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Szilvia Déri,
Affiliation Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary
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Dániel Tóth,
Affiliation MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary
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Jouko Levijoki,
Affiliation Orion Pharma, Espoo, Finland
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Piero Pollesello,
Affiliation Orion Pharma, Espoo, Finland
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Tuula Koskelainen,
Affiliation Orion Pharma, Espoo, Finland
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Leena Otsomaa,
Affiliation Orion Pharma, Espoo, Finland
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András Tóth,
Affiliations Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary, MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary
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István Baczkó,
Affiliations Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary, Department of Pathophysiology, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania
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István Leprán,
Affiliation Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary
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Péter P. Nánási,
Affiliations Department of Physiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary, Department of Dental Physiology and Pharmacology, Faculty of Dentistry, University of Debrecen, Debrecen, Hungary
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Julius Gy Papp,
Affiliations Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary, MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary
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András Varró ,
¶‡ These authors share senior authorship on this work.
Affiliations Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary, MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary
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László Virág
* E-mail: varro.andras@med.u-szeged.hu
¶‡ These authors share senior authorship on this work.
Affiliations Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Szeged, Hungary, MTA-SZTE Research Group of Cardiovascular Pharmacology, Hungarian Academy of Sciences, Szeged, Hungary
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The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments
- Zsófia Kohajda,
- Nikolett Farkas-Morvay,
- Norbert Jost,
- Norbert Nagy,
- Amir Geramipour,
- András Horváth,
- Richárd S. Varga,
- Tibor Hornyik,
- Claudia Corici,
- Károly Acsai
- Published: November 10, 2016
- https://doi.org/10.1371/journal.pone.0166041