Modelling Robust Feedback Control Mechanisms That Ensure Reliable Coordination of Histone Gene Expression with DNA Replication

Andrea Christopher; Heike Hameister; Holly Corrigall; Oliver Ebenhöh; Berndt Müller; Ekkehard Ullner

doi:10.1371/journal.pone.0165848

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Peer-reviewed

Research Article

Modelling Robust Feedback Control Mechanisms That Ensure Reliable Coordination of Histone Gene Expression with DNA Replication

Andrea Christopher ,

Contributed equally to this work with: Andrea Christopher, Heike Hameister

Affiliation School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen Foresterhill, Aberdeen, Scotland, United Kingdom
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Heike Hameister ,

Contributed equally to this work with: Andrea Christopher, Heike Hameister

Current address: Merck Serono GmbH, Darmstadt, Germany

Affiliation Department of Physics (SUPA) and Institute for Complex Systems and Mathematical Biology (ICSMB), University of Aberdeen, Aberdeen, Scotland, United Kingdom
⨯
Holly Corrigall,

Affiliation School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen Foresterhill, Aberdeen, Scotland, United Kingdom
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Oliver Ebenhöh ,

* E-mail: oliver.ebenhoeh@hhu.de (OE); b.mueller@abdn.ac.uk (BM); e.ullner@abdn.ac.uk (EU)

Affiliations School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen Foresterhill, Aberdeen, Scotland, United Kingdom, Institute of Quantitative and Theoretical Biology, Cluster of Excellence on Plant Sciences (CEPLAS), Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany
⨯
Berndt Müller ,

* E-mail: oliver.ebenhoeh@hhu.de (OE); b.mueller@abdn.ac.uk (BM); e.ullner@abdn.ac.uk (EU)

Affiliation School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen Foresterhill, Aberdeen, Scotland, United Kingdom
⨯
Ekkehard Ullner

* E-mail: oliver.ebenhoeh@hhu.de (OE); b.mueller@abdn.ac.uk (BM); e.ullner@abdn.ac.uk (EU)

Affiliations School of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, University of Aberdeen Foresterhill, Aberdeen, Scotland, United Kingdom, Department of Physics (SUPA) and Institute for Complex Systems and Mathematical Biology (ICSMB), University of Aberdeen, Aberdeen, Scotland, United Kingdom

http://orcid.org/0000-0002-6306-4218

⨯

Modelling Robust Feedback Control Mechanisms That Ensure Reliable Coordination of Histone Gene Expression with DNA Replication

Andrea Christopher,
Heike Hameister,
Holly Corrigall,
Oliver Ebenhöh,
Berndt Müller,
Ekkehard Ullner

Published: October 31, 2016
https://doi.org/10.1371/journal.pone.0165848

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Histones
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DNA-binding proteins
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Gene expression
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DNA replication
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Synthesis phase
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DNA synthesis
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Cell cycle and cell division
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RNA synthesis
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