SIRT6 Depletion Suppresses Tumor Growth by Promoting Cellular Senescence Induced by DNA Damage in HCC

• Namgyu Lee,

  Current address: Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

  Affiliation Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, Korea

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• Hye Guk Ryu,

  Affiliation Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, Korea

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• Jung-Hee Kwon,

  Affiliation Cbs Bioscience Inc., Daejeon, Korea

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• Dae-Kyum Kim,

  Affiliations Donnelly Centre, Departments of Molecular Genetics and Computer Science, University of Toronto, Toronto, Ontario, Canada, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

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• Sae Rom Kim,

  Affiliation Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, Korea

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• Hee Jung Wang,

  Affiliation Department of Surgery, Ajou University School of Medicine, Suwon, Korea

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• Kyong-Tai Kim,

  Affiliations Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, Korea, Division of Integrative Biosciences & Biotechnology, Pohang University of Science and Technology, Pohang, Gyeongbuk, Republic of Korea

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• Kwan Yong Choi

  * E-mail: kchoi@postech.ac.kr

  Affiliations Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk, Korea, Division of Integrative Biosciences & Biotechnology, Pohang University of Science and Technology, Pohang, Gyeongbuk, Republic of Korea

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