Disruption of Higher Order DNA Structures in Friedreich’s Ataxia (GAA)_n Repeats by PNA or LNA Targeting

• Helen Bergquist,

  Affiliations Department of Medical Biochemistry and Microbiology, Microbiology-Immunology, Uppsala University, Uppsala, Sweden, Department of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, SE-141 86, Huddinge, Sweden

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• Cristina S. J. Rocha,

  Affiliation Department of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, SE-141 86, Huddinge, Sweden

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• Rubén Álvarez-Asencio,

  Current address: Fundación IMDEA Nanociencia, Faraday, 9, Campus Universitario de Cantoblanco, Madrid, Spain.

  Affiliation KTH Royal Institute of Technology, School of Chemical Science and Engineering, Department of Chemistry, Stockholm, Sweden

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• Chi-Hung Nguyen,

  Affiliation Laboratoire de Pharmacochimie, Institut Curie, PSL Research University, UMR 9187 – U 1196 CNRS-Institut Curie, INSERM, Centre Universitaire, Orsay, France

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• Mark. W. Rutland,

  Affiliation KTH Royal Institute of Technology, School of Chemical Science and Engineering, Department of Chemistry, Stockholm, Sweden

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• C. I. Edvard Smith,

  Affiliation Department of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, SE-141 86, Huddinge, Sweden

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• Liam Good,

  Affiliation Department of Pathology and Infectious Diseases, Royal Veterinary College, University of London, United Kingdom

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• Peter E. Nielsen,

  Affiliation Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, The Panum Institute, Copenhagen, Denmark

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• Rula Zain

  * E-mail: rula.zain@ki.se

  Affiliations Department of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, SE-141 86, Huddinge, Sweden, Department of Clinical Genetics, Centre for Rare Diseases, Karolinska University Hospital, SE-171 76, Stockholm, Sweden

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