CDH1 Missense Variant c.1679C>G (p.T560R) Completely Disrupts Normal Splicing through Creation of a Novel 5’ Splice Site

Zarina Yelskaya; Ruben Bacares; Erin Salo-Mullen; Joshua Somar; Deborah A. Lehrich; Grace-Ann Fasaye; Daniel G. Coit; Laura H. Tang; Zsofia K. Stadler; Liying Zhang

doi:10.1371/journal.pone.0165654

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Open Access

Peer-reviewed

Research Article

CDH1 Missense Variant c.1679C>G (p.T560R) Completely Disrupts Normal Splicing through Creation of a Novel 5’ Splice Site

Zarina Yelskaya,

Affiliation Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

http://orcid.org/0000-0003-4517-0751

⨯
Ruben Bacares,

Affiliation Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Erin Salo-Mullen,

Affiliation Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Joshua Somar,

Affiliation Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Deborah A. Lehrich,

Affiliation Department of Hematology Oncology, Walter Reed National Military Medical Center, Bethesda, Maryland, United States of America
⨯
Grace-Ann Fasaye,

Affiliation Department of Surgical Oncology, Walter Reed National Military Medical Center, Bethesda, Maryland, United States of America
⨯
Daniel G. Coit,

Affiliation Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Laura H. Tang,

Affiliation Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Zsofia K. Stadler,

Affiliation Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Liying Zhang

* E-mail: ZHANGL2@MSKCC.ORG

Affiliation Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯

CDH1 Missense Variant c.1679C>G (p.T560R) Completely Disrupts Normal Splicing through Creation of a Novel 5’ Splice Site

Zarina Yelskaya,
Ruben Bacares,
Erin Salo-Mullen,
Joshua Somar,
Deborah A. Lehrich,
Grace-Ann Fasaye,
Daniel G. Coit,
Laura H. Tang,
Zsofia K. Stadler,
Liying Zhang

Published: November 23, 2016
https://doi.org/10.1371/journal.pone.0165654

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