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Open Access
Peer-reviewed
Research Article
Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis
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Karianne Fjeld ,
Contributed equally to this work with: Karianne Fjeld, Sebastian Beer, Marianne Johnstone, William Greenhalf, Anders Molven, Robert Sutton, Jonas Rosendahl
Affiliations KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway
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Sebastian Beer ,
Contributed equally to this work with: Karianne Fjeld, Sebastian Beer, Marianne Johnstone, William Greenhalf, Anders Molven, Robert Sutton, Jonas Rosendahl
Affiliation Department of Internal Medicine, Neurology and Dermatology, Division of Gastroenterology and Rheumatology, University of Leipzig, Leipzig, Germany
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Marianne Johnstone ,
Contributed equally to this work with: Karianne Fjeld, Sebastian Beer, Marianne Johnstone, William Greenhalf, Anders Molven, Robert Sutton, Jonas Rosendahl
Affiliation NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
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Constantin Zimmer,
Affiliation Department of Internal Medicine, Neurology and Dermatology, Division of Gastroenterology and Rheumatology, University of Leipzig, Leipzig, Germany
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Joachim Mössner,
Affiliation Department of Internal Medicine, Neurology and Dermatology, Division of Gastroenterology and Rheumatology, University of Leipzig, Leipzig, Germany
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Claudia Ruffert,
Affiliation Department of Internal Medicine I, Martin Luther University, Halle, Germany
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Mario Krehan,
Affiliation Department of Internal Medicine, Neurology and Dermatology, Division of Gastroenterology and Rheumatology, University of Leipzig, Leipzig, Germany
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Christian Zapf,
Affiliation Department of Internal Medicine, Neurology and Dermatology, Division of Gastroenterology and Rheumatology, University of Leipzig, Leipzig, Germany
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Pål Rasmus Njølstad,
Affiliations KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway, Department of Pediatrics, Haukeland University Hospital, Bergen, Norway
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Stefan Johansson,
Affiliations KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway
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Peter Bugert,
Affiliation Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, German Red Cross Blood Service of Baden-Württemberg-Hessen, Mannheim, Germany
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Fabio Miyajima,
Affiliation Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
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Triantafillos Liloglou,
Affiliation Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
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Laura J. Brown,
Affiliation NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
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Simon A. Winn,
Affiliation NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
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Kelly Davies,
Affiliation NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
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Diane Latawiec,
Affiliation NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
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Bridget K. Gunson,
Affiliation NIHR Birmingham Liver Biomedical Research Unit, Queen Elizabeth Hospital and University of Birmingham, Birmingham, United Kingdom
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David N. Criddle,
Affiliation Department of Cellular & Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
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Munir Pirmohamed,
Affiliation Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
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Robert Grützmann,
Affiliation Department of Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
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Patrick Michl,
Affiliation Department of Internal Medicine I, Martin Luther University, Halle, Germany
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William Greenhalf ,
Contributed equally to this work with: Karianne Fjeld, Sebastian Beer, Marianne Johnstone, William Greenhalf, Anders Molven, Robert Sutton, Jonas Rosendahl
Affiliation NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
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Anders Molven ,
Contributed equally to this work with: Karianne Fjeld, Sebastian Beer, Marianne Johnstone, William Greenhalf, Anders Molven, Robert Sutton, Jonas Rosendahl
Affiliations KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway, Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, Bergen, Norway, Department of Pathology, Haukeland University Hospital, Bergen, Norway
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Robert Sutton ,
Contributed equally to this work with: Karianne Fjeld, Sebastian Beer, Marianne Johnstone, William Greenhalf, Anders Molven, Robert Sutton, Jonas Rosendahl
Affiliation NIHR Liverpool Pancreas Biomedical Research Unit, Royal Liverpool University Hospital, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
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Jonas Rosendahl
Contributed equally to this work with: Karianne Fjeld, Sebastian Beer, Marianne Johnstone, William Greenhalf, Anders Molven, Robert Sutton, Jonas Rosendahl
* E-mail: jonas.rosendahl@uk-halle.de
Affiliation Department of Internal Medicine I, Martin Luther University, Halle, Germany
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Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis
- Karianne Fjeld,
- Sebastian Beer,
- Marianne Johnstone,
- Constantin Zimmer,
- Joachim Mössner,
- Claudia Ruffert,
- Mario Krehan,
- Christian Zapf,
- Pål Rasmus Njølstad,
- Stefan Johansson
- Published: November 1, 2016
- https://doi.org/10.1371/journal.pone.0165567