Characterization of Autoantigens Targeted by Anti-Citrullinated Protein Antibodies In Vivo: Prominent Role for Epitopes Derived from Histone 4 Proteins

• Xiaobo Meng,

  Affiliations Arthritis Centre, Department of Internal Medicine, University of Manitoba, RR149, 800 Sherbrook St. Winnipeg, MB, R3A 1M4, Canada, Manitoba Centre for Proteomics and Systems Biology, University of Manitoba, 799 JBRC, 715 McDermot Ave, Winnipeg, MB, R3E 3P4, Canada

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• Peyman Ezzati,

  Affiliation Manitoba Centre for Proteomics and Systems Biology, University of Manitoba, 799 JBRC, 715 McDermot Ave, Winnipeg, MB, R3E 3P4, Canada

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• Irene Smolik,

  Affiliation Arthritis Centre, Department of Internal Medicine, University of Manitoba, RR149, 800 Sherbrook St. Winnipeg, MB, R3A 1M4, Canada

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• Charles N. Bernstein,

  Affiliation Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada

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• Carol Ann Hitchon,

  Affiliation Arthritis Centre, Department of Internal Medicine, University of Manitoba, RR149, 800 Sherbrook St. Winnipeg, MB, R3A 1M4, Canada

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• Hani S. El-Gabalawy

  * E-mail: Hani.elgabalawy@umanitoba.ca

  Affiliations Arthritis Centre, Department of Internal Medicine, University of Manitoba, RR149, 800 Sherbrook St. Winnipeg, MB, R3A 1M4, Canada, Manitoba Centre for Proteomics and Systems Biology, University of Manitoba, 799 JBRC, 715 McDermot Ave, Winnipeg, MB, R3E 3P4, Canada

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