Effect of Transplanting Various Concentrations of a Composite of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells and Hyaluronic Acid Hydrogel on Articular Cartilage Repair in a Rabbit Model

Yong-Beom Park; Chul-Won Ha; Jin-A Kim; Ji-Heon Rhim; Yong-Geun Park; Jun Young Chung; Han-Jun Lee

doi:10.1371/journal.pone.0165446

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Open Access

Peer-reviewed

Research Article

Effect of Transplanting Various Concentrations of a Composite of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells and Hyaluronic Acid Hydrogel on Articular Cartilage Repair in a Rabbit Model

Yong-Beom Park,

Affiliation Department of Orthopedic Surgery, Chung-Ang University Hospital, Chung-Ang University College of Medicine, 102 Heukseok-ro, Dongjak-gu, Seoul 06973, South Korea

http://orcid.org/0000-0002-3741-2311

⨯
Chul-Won Ha ,

* E-mail: chulwon.ha@gmail.com, hacw@skku.edu

Affiliations Department of Orthopaedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, South Korea, Stem Cell & Regenerative Medicine Research Institute, Samsung Medical Center, 81 Irwon-ro, Gangnam-gu, Seoul 06351, South Korea, Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, South Korea
⨯
Jin-A Kim,

Affiliations Department of Orthopaedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, South Korea, Stem Cell & Regenerative Medicine Research Institute, Samsung Medical Center, 81 Irwon-ro, Gangnam-gu, Seoul 06351, South Korea
⨯
Ji-Heon Rhim,

Affiliations Department of Orthopaedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, South Korea, Stem Cell & Regenerative Medicine Research Institute, Samsung Medical Center, 81 Irwon-ro, Gangnam-gu, Seoul 06351, South Korea
⨯
Yong-Geun Park,

Affiliation Department of Orthopedic Surgery, Jeju National University Hospital, Jeju National University School of Medicine, 15 Aran 13-gil, Jeju-si 63241, South Korea
⨯
Jun Young Chung,

Affiliation Department of Orthopaedic Surgery, Ajou University Hospital, Ajou University School of Medicine, 164 World cup-ro, Yeongtong-gu, Suwon 16499, South Korea
⨯
Han-Jun Lee

Affiliation Department of Orthopedic Surgery, Chung-Ang University Hospital, Chung-Ang University College of Medicine, 102 Heukseok-ro, Dongjak-gu, Seoul 06973, South Korea
⨯

Effect of Transplanting Various Concentrations of a Composite of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells and Hyaluronic Acid Hydrogel on Articular Cartilage Repair in a Rabbit Model

Yong-Beom Park,
Chul-Won Ha,
Jin-A Kim,
Ji-Heon Rhim,
Yong-Geun Park,
Jun Young Chung,
Han-Jun Lee

Published: November 8, 2016
https://doi.org/10.1371/journal.pone.0165446

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