Prefrontal Activity and Connectivity with the Basal Ganglia during Performance of Complex Cognitive Tasks Is Associated with Apathy in Healthy Subjects

• Leonardo Fazio,

  Affiliations University of Bari ‘Aldo Moro’—Department of Basic Medical Science, Neuroscience, and Sense Organs, 70124, Bari, Italy, IRCCS “Casa Sollievo della Sofferenza”, 71013, San Giovanni Rotondo, Italy

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• Giancarlo Logroscino,

  Affiliation University of Bari ‘Aldo Moro’—Department of Basic Medicine, Neuroscience, and Sense Organs, 70124 Bari, Italy and University of Bari ‘Aldo Moro’, “Pia Fondazione Cardinale G. Panico”—Department of Clinical Research in Neurology, 73039 Tricase, Lecce, Italy

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• Paolo Taurisano,

  Affiliation University of Bari ‘Aldo Moro’—Department of Basic Medical Science, Neuroscience, and Sense Organs, 70124, Bari, Italy

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• Graziella Amico,

  Affiliation University of Bari ‘Aldo Moro’—Department of Basic Medical Science, Neuroscience, and Sense Organs, 70124, Bari, Italy

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• Tiziana Quarto,

  Affiliation University of Bari ‘Aldo Moro’—Department of Basic Medical Science, Neuroscience, and Sense Organs, 70124, Bari, Italy

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• Linda Antonella Antonucci,

  Affiliation University of Bari ‘Aldo Moro’—Department of Basic Medical Science, Neuroscience, and Sense Organs, 70124, Bari, Italy

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• Maria Rosaria Barulli,

  Affiliation University of Bari ‘Aldo Moro’—Department of Basic Medicine, Neuroscience, and Sense Organs, 70124 Bari, Italy and University of Bari ‘Aldo Moro’, “Pia Fondazione Cardinale G. Panico”—Department of Clinical Research in Neurology, 73039 Tricase, Lecce, Italy

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• Marina Mancini,

  Affiliation University of Bari ‘Aldo Moro’—Department of Basic Medical Science, Neuroscience, and Sense Organs, 70124, Bari, Italy

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• Barbara Gelao,

  Affiliation University of Bari ‘Aldo Moro’—Department of Basic Medical Science, Neuroscience, and Sense Organs, 70124, Bari, Italy

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• Laura Ferranti,

  Affiliation University of Perugia—Department of General and Experimental Medicine, 06123, Perugia, Italy

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• Teresa Popolizio,

  Affiliation IRCCS “Casa Sollievo della Sofferenza”, 71013, San Giovanni Rotondo, Italy

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• Alessandro Bertolino,

  Affiliations University of Bari ‘Aldo Moro’—Department of Basic Medical Science, Neuroscience, and Sense Organs, 70124, Bari, Italy, Bari University Hospital—Psychiatry Unit, 70124, Bari, Italy

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• Giuseppe Blasi

  * E-mail: blasi.seppe@gmail.com

  Affiliation Bari University Hospital—Psychiatry Unit, 70124, Bari, Italy

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