Frontal Lobe Hemodynamic Responses to Painful Stimulation: A Potential Brain Marker of Nociception

• Christopher M. Aasted ,

  Contributed equally to this work with: Christopher M. Aasted, Meryem A. Yücel

  Affiliations Center for Pain and the Brain, Harvard Medical School; Boston, Massachusetts, United States of America, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children’s Hospital and Harvard Medical School; Boston, Massachusetts, United States of America, Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School; Boston, Massachusetts, United States of America

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• Meryem A. Yücel ,

  Contributed equally to this work with: Christopher M. Aasted, Meryem A. Yücel

  Affiliation Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School; Boston, Massachusetts, United States of America

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• Sarah C. Steele,

  Affiliations Center for Pain and the Brain, Harvard Medical School; Boston, Massachusetts, United States of America, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children’s Hospital and Harvard Medical School; Boston, Massachusetts, United States of America, Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School; Boston, Massachusetts, United States of America

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• Ke Peng,

  Affiliations Center for Pain and the Brain, Harvard Medical School; Boston, Massachusetts, United States of America, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children’s Hospital and Harvard Medical School; Boston, Massachusetts, United States of America, Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School; Boston, Massachusetts, United States of America

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• David A. Boas,

  Affiliation Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School; Boston, Massachusetts, United States of America

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• Lino Becerra,

  Affiliations Center for Pain and the Brain, Harvard Medical School; Boston, Massachusetts, United States of America, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children’s Hospital and Harvard Medical School; Boston, Massachusetts, United States of America, Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School; Boston, Massachusetts, United States of America

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• David Borsook

  * E-mail: david.borsook@childrens.harvard.edu

  Affiliations Center for Pain and the Brain, Harvard Medical School; Boston, Massachusetts, United States of America, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children’s Hospital and Harvard Medical School; Boston, Massachusetts, United States of America, Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School; Boston, Massachusetts, United States of America

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