Reproducibility of Digital PCR Assays for Circulating Tumor DNA Analysis in Advanced Breast Cancer

Sarah Hrebien; Ben O’Leary; Matthew Beaney; Gaia Schiavon; Charlotte Fribbens; Amarjit Bhambra; Richard Johnson; Isaac Garcia-Murillas; Nicholas Turner

doi:10.1371/journal.pone.0165023

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Open Access

Peer-reviewed

Research Article

Reproducibility of Digital PCR Assays for Circulating Tumor DNA Analysis in Advanced Breast Cancer

Sarah Hrebien,

Affiliation The Breast Cancer Now Research Centre, The Institute of Cancer Research, London, SW3 6JB, United Kingdom
⨯
Ben O’Leary,

Affiliations The Breast Cancer Now Research Centre, The Institute of Cancer Research, London, SW3 6JB, United Kingdom, Breast Unit, Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, United Kingdom
⨯
Matthew Beaney,

Affiliation The Breast Cancer Now Research Centre, The Institute of Cancer Research, London, SW3 6JB, United Kingdom
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Gaia Schiavon,

Affiliation Translational Science, Oncology iMed, AstraZeneca, Cambridge, CB4 0WG, United Kingdom
⨯
Charlotte Fribbens,

Affiliations The Breast Cancer Now Research Centre, The Institute of Cancer Research, London, SW3 6JB, United Kingdom, Breast Unit, Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, United Kingdom
⨯
Amarjit Bhambra,

Affiliation Breast Unit, Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, United Kingdom
⨯
Richard Johnson,

Affiliation Breast Unit, Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, United Kingdom
⨯
Isaac Garcia-Murillas,

Affiliation The Breast Cancer Now Research Centre, The Institute of Cancer Research, London, SW3 6JB, United Kingdom

http://orcid.org/0000-0001-8183-7969

⨯
Nicholas Turner

* E-mail: nicholas.turner@icr.ac.uk

Affiliations The Breast Cancer Now Research Centre, The Institute of Cancer Research, London, SW3 6JB, United Kingdom, Breast Unit, Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, United Kingdom
⨯

Reproducibility of Digital PCR Assays for Circulating Tumor DNA Analysis in Advanced Breast Cancer

Sarah Hrebien,
Ben O’Leary,
Matthew Beaney,
Gaia Schiavon,
Charlotte Fribbens,
Amarjit Bhambra,
Richard Johnson,
Isaac Garcia-Murillas,
Nicholas Turner

Published: October 19, 2016
https://doi.org/10.1371/journal.pone.0165023

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Blood plasma
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