Multiple Evolutionary Origins of Ubiquitous Cu2+ and Zn2+ Binding in the S100 Protein Family

Open Access

Peer-reviewed

Research Article

Multiple Evolutionary Origins of Ubiquitous Cu²⁺ and Zn²⁺ Binding in the S100 Protein Family

Lucas C. Wheeler,

Affiliations Department of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon, 97403, United States of America, Institute for Molecular Biology, University of Oregon, Eugene, Oregon, 97403, United States of America
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Micah T. Donor,

Affiliation Department of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon, 97403, United States of America
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James S. Prell,

Affiliation Department of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon, 97403, United States of America
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Michael J. Harms

* E-mail: harms@uoregon.edu

Affiliations Department of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon, 97403, United States of America, Institute for Molecular Biology, University of Oregon, Eugene, Oregon, 97403, United States of America

http://orcid.org/0000-0002-0241-4122

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Phylogenetic analysis
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Transition metals
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Tunicata
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Dimers
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Animal phylogenetics
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Sequence alignment
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Stoichiometry
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Taxonomy
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