Bmi1 Loss in the Organ of Corti Results in p16ink4a Upregulation and Reduced Cell Proliferation of Otic Progenitors In Vitro

Open Access

Peer-reviewed

Research Article

Bmi1 Loss in the Organ of Corti Results in p16^ink4a Upregulation and Reduced Cell Proliferation of Otic Progenitors In Vitro

Mohamed Bassiouni,

Affiliation Department of Otolaryngology, Head and Neck Surgery, Tübingen Hearing Research Centre, Eberhard Karls University Tübingen, Tübingen, Germany

http://orcid.org/0000-0002-9056-885X

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Aurélie Dos Santos,

Affiliation Department of Otolaryngology, Head and Neck Surgery, Tübingen Hearing Research Centre, Eberhard Karls University Tübingen, Tübingen, Germany
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Hasan X. Avci,

Affiliation Department of Otolaryngology, Head and Neck Surgery, Tübingen Hearing Research Centre, Eberhard Karls University Tübingen, Tübingen, Germany
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Hubert Löwenheim,

Affiliation Department of Otolaryngology, Head and Neck Surgery, Tübingen Hearing Research Centre, Eberhard Karls University Tübingen, Tübingen, Germany
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Marcus Müller

* E-mail: marcus.mueller@uni-tuebingen.de

Affiliation Department of Otolaryngology, Head and Neck Surgery, Tübingen Hearing Research Centre, Eberhard Karls University Tübingen, Tübingen, Germany
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Cell cycle and cell division
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Cochlea
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Cell proliferation
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Stem cells
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Organ of Corti
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Messenger RNA
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Sensory perception
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Viral vectors
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