Objectives and Design of BLEEDS: A Cohort Study to Identify New Risk Factors and Predictors for Major Bleeding during Treatment with Vitamin K Antagonists

• Nienke van Rein ,

  * E-mail: n.van_rein@lumc.nl

  Affiliations Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands

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• Willem M. Lijfering,

  Affiliations Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands, Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands

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• Mettine H. A. Bos,

  Affiliations Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands

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• Martien H. Herruer,

  Affiliation Atalmedial Medical Diagnostic Centers, Hoofddorp, the Netherlands

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• Helga W. Vermaas,

  Affiliation Anticoagulation Clinic the Hague, The Hague, the Netherlands

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• Felix J. M. van der Meer,

  Affiliation Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands

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• Pieter H. Reitsma

  Affiliations Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands

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