Chemical Compensation of Mitochondrial Phospholipid Depletion in Yeast and Animal Models of Parkinson’s Disease

Shaoxiao Wang; Siyuan Zhang; Chuan Xu; Addie Barron; Floyd Galiano; Dhaval Patel; Yong Joo Lee; Guy A. Caldwell; Kim A. Caldwell; Stephan N. Witt

doi:10.1371/journal.pone.0164465

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Open Access

Peer-reviewed

Research Article

Chemical Compensation of Mitochondrial Phospholipid Depletion in Yeast and Animal Models of Parkinson’s Disease

Shaoxiao Wang ,

¶‡ These authors are co-first authors on this work.

Affiliation Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA, United States of America
⨯
Siyuan Zhang ,

¶‡ These authors are co-first authors on this work.

Affiliation Department of Biological Sciences, The University of Alabama, Tuscaloosa, AL, United States of America
⨯
Chuan Xu ,

¶‡ These authors are co-first authors on this work.

Affiliation Department of Biological Sciences, The University of Alabama, Tuscaloosa, AL, United States of America
⨯
Addie Barron,

Affiliation Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA, United States of America
⨯
Floyd Galiano,

Affiliation Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA, United States of America
⨯
Dhaval Patel,

Affiliation Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA, United States of America
⨯
Yong Joo Lee,

Affiliation Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA, United States of America
⨯
Guy A. Caldwell,

Affiliation Department of Biological Sciences, The University of Alabama, Tuscaloosa, AL, United States of America
⨯
Kim A. Caldwell,

Affiliation Department of Biological Sciences, The University of Alabama, Tuscaloosa, AL, United States of America
⨯
Stephan N. Witt

* E-mail: switt1@lsuhsc.edu

Affiliations Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA, United States of America, Department of Pharmacology, Toxicology and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA, United States of America

http://orcid.org/0000-0002-6462-2840

⨯

Chemical Compensation of Mitochondrial Phospholipid Depletion in Yeast and Animal Models of Parkinson’s Disease

Shaoxiao Wang,
Siyuan Zhang,
Chuan Xu,
Addie Barron,
Floyd Galiano,
Dhaval Patel,
Yong Joo Lee,
Guy A. Caldwell,
Kim A. Caldwell,
Stephan N. Witt

Published: October 13, 2016
https://doi.org/10.1371/journal.pone.0164465

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