8-Oxoguanine Affects DNA Backbone Conformation in the EcoRI Recognition Site and Inhibits Its Cleavage by the Enzyme

• Joanna J. Hoppins ,

  Contributed equally to this work with: Joanna J. Hoppins, David R. Gruber, Heather L. Miears

  Affiliation Chemistry Department, Western Washington University, Bellingham, WA, United States of America

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• David R. Gruber ,

  Contributed equally to this work with: Joanna J. Hoppins, David R. Gruber, Heather L. Miears

  Affiliation Chemistry Department, Western Washington University, Bellingham, WA, United States of America

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• Heather L. Miears ,

  Contributed equally to this work with: Joanna J. Hoppins, David R. Gruber, Heather L. Miears

  Affiliation Chemistry Department, Western Washington University, Bellingham, WA, United States of America

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• Alexey S. Kiryutin,

  Affiliations SB RAS International Tomography Center, Novosibirsk, Russia, Novosibirsk State University, Novosibirsk, Russia

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• Rustem D. Kasymov,

  Affiliations SB RAS Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia, Institute of Biochemistry, Stuttgart University, Stuttgart, Germany

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• Darya V. Petrova,

  Affiliations Novosibirsk State University, Novosibirsk, Russia, SB RAS Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia

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• Anton V. Endutkin,

  Affiliations Novosibirsk State University, Novosibirsk, Russia, SB RAS Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia

  ⨯
• Alexander V. Popov,

  Affiliation SB RAS Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia

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• Alexandra V. Yurkovskaya,

  Affiliations SB RAS International Tomography Center, Novosibirsk, Russia, Novosibirsk State University, Novosibirsk, Russia

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• Stanislav O. Fedechkin,

  Affiliations Chemistry Department, Western Washington University, Bellingham, WA, United States of America, University of California Santa Cruz, Program in Biomedical Science and Engineering, Santa Cruz, CA, United States of America

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• Jacob A. Brockerman,

  Affiliations Chemistry Department, Western Washington University, Bellingham, WA, United States of America, Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada

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• Dmitry O. Zharkov ,

  * E-mail: sergey.smirnov@wwu.edu (SLS); dzharkov@niboch.nsc.ru (DOZ)

  Affiliations Novosibirsk State University, Novosibirsk, Russia, SB RAS Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia

  ⨯
• Serge L. Smirnov

  * E-mail: sergey.smirnov@wwu.edu (SLS); dzharkov@niboch.nsc.ru (DOZ)

  Affiliation Chemistry Department, Western Washington University, Bellingham, WA, United States of America

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