Increased Abundance of Proteins Involved in Resistance to Oxidative and Nitrosative Stress at the Last Stages of Growth and Development of Leishmania amazonensis Promastigotes Revealed by Proteome Analysis

Pedro J. Alcolea; Ana Alonso; Francisco García-Tabares; María C. Mena; Sergio Ciordia; Vicente Larraga

doi:10.1371/journal.pone.0164344

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Research Article

Increased Abundance of Proteins Involved in Resistance to Oxidative and Nitrosative Stress at the Last Stages of Growth and Development of Leishmania amazonensis Promastigotes Revealed by Proteome Analysis

Pedro J. Alcolea ,

* E-mail: pjalcolea@cib.csic.es

Affiliation Departamento de Microbiología Molecular y Biología de las Infecciones y Servicio de Proteómica y Genómica, Centro de Investigaciones Biológicas (Consejo Superior de Investigaciones Científicas), Calle Ramiro de Maeztu 9, 28040, Madrid, Spain

http://orcid.org/0000-0002-0729-8941

⨯
Ana Alonso,

Affiliation Departamento de Microbiología Molecular y Biología de las Infecciones y Servicio de Proteómica y Genómica, Centro de Investigaciones Biológicas (Consejo Superior de Investigaciones Científicas), Calle Ramiro de Maeztu 9, 28040, Madrid, Spain
⨯
Francisco García-Tabares,

Affiliation Departamento de Microbiología Molecular y Biología de las Infecciones y Servicio de Proteómica y Genómica, Centro de Investigaciones Biológicas (Consejo Superior de Investigaciones Científicas), Calle Ramiro de Maeztu 9, 28040, Madrid, Spain
⨯
María C. Mena,

Affiliation Unidad de Proteómica, Centro Nacional de Biotecnología (Consejo Superior de Investigaciones Científicas), Calle Darwin 3, 28049, Madrid, Spain
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Sergio Ciordia,

Affiliation Unidad de Proteómica, Centro Nacional de Biotecnología (Consejo Superior de Investigaciones Científicas), Calle Darwin 3, 28049, Madrid, Spain
⨯
Vicente Larraga

Affiliation Departamento de Microbiología Molecular y Biología de las Infecciones y Servicio de Proteómica y Genómica, Centro de Investigaciones Biológicas (Consejo Superior de Investigaciones Científicas), Calle Ramiro de Maeztu 9, 28040, Madrid, Spain
⨯

Increased Abundance of Proteins Involved in Resistance to Oxidative and Nitrosative Stress at the Last Stages of Growth and Development of Leishmania amazonensis Promastigotes Revealed by Proteome Analysis

Pedro J. Alcolea,
Ana Alonso,
Francisco García-Tabares,
María C. Mena,
Sergio Ciordia,
Vicente Larraga

Published: October 24, 2016
https://doi.org/10.1371/journal.pone.0164344

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Promastigotes
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Leishmania infantum
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Amastigotes
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Nitric oxide
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Leishmania
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Cell differentiation
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Proteases
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