MMP-2 Isoforms in Aortic Tissue and Serum of Patients with Ascending Aortic Aneurysms and Aortic Root Aneurysms

Anke Tscheuschler; Philipp Meffert; Friedhelm Beyersdorf; Claudia Heilmann; Nadja Kocher; Xenia Uffelmann; Philipp Discher; Matthias Siepe; Fabian A. Kari

doi:10.1371/journal.pone.0164308

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Open Access

Peer-reviewed

Research Article

MMP-2 Isoforms in Aortic Tissue and Serum of Patients with Ascending Aortic Aneurysms and Aortic Root Aneurysms

Anke Tscheuschler ,

* E-mail: anke.tscheuschler@uniklinik-freiburg.de

Affiliations Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Freiburg, Germany, Working Group on Molecular and Cellular Pathophysiology in Thoracic Aortic Disease, Dr. Barbara-Mez-Starck Cardiovascular Research Laboratory, Heart Center, University of Freiburg, Freiburg, Germany
⨯
Philipp Meffert,

Affiliations Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Freiburg, Germany, Working Group on Molecular and Cellular Pathophysiology in Thoracic Aortic Disease, Dr. Barbara-Mez-Starck Cardiovascular Research Laboratory, Heart Center, University of Freiburg, Freiburg, Germany
⨯
Friedhelm Beyersdorf,

Affiliation Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Freiburg, Germany
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Claudia Heilmann,

Affiliations Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Freiburg, Germany, Working Group on Molecular and Cellular Pathophysiology in Thoracic Aortic Disease, Dr. Barbara-Mez-Starck Cardiovascular Research Laboratory, Heart Center, University of Freiburg, Freiburg, Germany
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Nadja Kocher,

Affiliations Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Freiburg, Germany, Working Group on Molecular and Cellular Pathophysiology in Thoracic Aortic Disease, Dr. Barbara-Mez-Starck Cardiovascular Research Laboratory, Heart Center, University of Freiburg, Freiburg, Germany
⨯
Xenia Uffelmann,

Affiliations Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Freiburg, Germany, Working Group on Molecular and Cellular Pathophysiology in Thoracic Aortic Disease, Dr. Barbara-Mez-Starck Cardiovascular Research Laboratory, Heart Center, University of Freiburg, Freiburg, Germany
⨯
Philipp Discher,

Affiliations Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Freiburg, Germany, Working Group on Molecular and Cellular Pathophysiology in Thoracic Aortic Disease, Dr. Barbara-Mez-Starck Cardiovascular Research Laboratory, Heart Center, University of Freiburg, Freiburg, Germany
⨯
Matthias Siepe,

Affiliation Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Freiburg, Germany
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Fabian A. Kari

Affiliations Department of Cardiovascular Surgery, Heart Center, University of Freiburg, Freiburg, Germany, Working Group on Molecular and Cellular Pathophysiology in Thoracic Aortic Disease, Dr. Barbara-Mez-Starck Cardiovascular Research Laboratory, Heart Center, University of Freiburg, Freiburg, Germany
⨯

MMP-2 Isoforms in Aortic Tissue and Serum of Patients with Ascending Aortic Aneurysms and Aortic Root Aneurysms

Anke Tscheuschler,
Philipp Meffert,
Friedhelm Beyersdorf,
Claudia Heilmann,
Nadja Kocher,
Xenia Uffelmann,
Philipp Discher,
Matthias Siepe,
Fabian A. Kari

Published: November 1, 2016
https://doi.org/10.1371/journal.pone.0164308

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Aneurysms
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Protein extraction
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Gelatin
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Aortic valve
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