Intrinsic Resistance to 5-Fluorouracil in a Brain Metastatic Variant of Human Breast Cancer Cell Line, MDA-MB-231BR

Atsunobu Sagara; Katsuhide Igarashi; Maky Otsuka; Takeshi Karasawa; Noriko Gotoh; Michiko Narita; Naoko Kuzumaki; Minoru Narita; Yoshinori Kato

doi:10.1371/journal.pone.0164250

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Peer-reviewed

Research Article

Intrinsic Resistance to 5-Fluorouracil in a Brain Metastatic Variant of Human Breast Cancer Cell Line, MDA-MB-231BR

Atsunobu Sagara,

Affiliation Department of Pharmacology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, 2-4-41 Ebara, Shinagawa-ku, Tokyo, Japan
⨯
Katsuhide Igarashi,

Affiliation Life Science Tokyo Advanced Research Center (L-StaR), Hoshi University School of Pharmacy and Pharmaceutical Sciences, 2-4-41 Ebara, Shinagawa-ku, Tokyo, Japan
⨯
Maky Otsuka,

Affiliation Life Science Tokyo Advanced Research Center (L-StaR), Hoshi University School of Pharmacy and Pharmaceutical Sciences, 2-4-41 Ebara, Shinagawa-ku, Tokyo, Japan
⨯
Takeshi Karasawa,

Affiliation Department of Pharmacology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, 2-4-41 Ebara, Shinagawa-ku, Tokyo, Japan
⨯
Noriko Gotoh,

Affiliation Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kakuma-machi, Kanazawa city, Ishikawa, Japan
⨯
Michiko Narita,

Affiliation Department of Pharmacology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, 2-4-41 Ebara, Shinagawa-ku, Tokyo, Japan
⨯
Naoko Kuzumaki,

Affiliation Department of Pharmacology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, 2-4-41 Ebara, Shinagawa-ku, Tokyo, Japan
⨯
Minoru Narita ,

* E-mail: y-kato@hoshi.ac.jp (YK); narita@hoshi.ac.jp (MN)

Affiliations Department of Pharmacology, Hoshi University School of Pharmacy and Pharmaceutical Sciences, 2-4-41 Ebara, Shinagawa-ku, Tokyo, Japan, Life Science Tokyo Advanced Research Center (L-StaR), Hoshi University School of Pharmacy and Pharmaceutical Sciences, 2-4-41 Ebara, Shinagawa-ku, Tokyo, Japan
⨯
Yoshinori Kato

* E-mail: y-kato@hoshi.ac.jp (YK); narita@hoshi.ac.jp (MN)

Affiliation Life Science Tokyo Advanced Research Center (L-StaR), Hoshi University School of Pharmacy and Pharmaceutical Sciences, 2-4-41 Ebara, Shinagawa-ku, Tokyo, Japan

http://orcid.org/0000-0002-6218-8710

⨯

Intrinsic Resistance to 5-Fluorouracil in a Brain Metastatic Variant of Human Breast Cancer Cell Line, MDA-MB-231BR

Atsunobu Sagara,
Katsuhide Igarashi,
Maky Otsuka,
Takeshi Karasawa,
Noriko Gotoh,
Michiko Narita,
Naoko Kuzumaki,
Minoru Narita,
Yoshinori Kato

Published: October 10, 2016
https://doi.org/10.1371/journal.pone.0164250

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Protein expression
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