The Effect of Prophylactic Lamivudine plus Adefovir Therapy Compared with Lamivudine Alone in Preventing Hepatitis B Reactivation in Lymphoma Patients with High Baseline HBV DNA during Chemotherapy

Qingqing Cai; Kailin Chen; Jie Chen; Shaoxu Wu; Qirong Geng; Huiqiang Huang; Tongyu Lin; Wenqi Jiang; Zhongjun Xia; Huaxin Duan; Huilan Rao; Mengfei Yao; Liyang Hu

doi:10.1371/journal.pone.0164210

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Open Access

Peer-reviewed

Research Article

The Effect of Prophylactic Lamivudine plus Adefovir Therapy Compared with Lamivudine Alone in Preventing Hepatitis B Reactivation in Lymphoma Patients with High Baseline HBV DNA during Chemotherapy

Qingqing Cai ,

Contributed equally to this work with: Qingqing Cai, Kailin Chen, Jie Chen

* E-mail: caiqq@sysucc.org.cn

Affiliation Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, P.R. China
⨯
Kailin Chen ,

Contributed equally to this work with: Qingqing Cai, Kailin Chen, Jie Chen

Affiliations Department of Oncology, Hunan Provincial People's Hospital, the First Affiliated Hospital of Hunan Normal University, Changsha, P.R. China, Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, P.R. China
⨯
Jie Chen ,

Contributed equally to this work with: Qingqing Cai, Kailin Chen, Jie Chen

Affiliation Guangdong Province Key Laboratory of Arrhythmia and Electrophysiology, Guangzhou, China, and Radiotherapy Department, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, P.R. China
⨯
Shaoxu Wu,

Affiliation Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, P.R. China
⨯
Qirong Geng,

Affiliation Department of hematology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, P.R. China
⨯
Huiqiang Huang,

Affiliation Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, P.R. China
⨯
Tongyu Lin,

Affiliation Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, P.R. China
⨯
Wenqi Jiang,

Affiliation Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, P.R. China
⨯
Zhongjun Xia,

Affiliation Department of hematology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, P.R. China
⨯
Huaxin Duan,

Affiliation Department of Oncology, Hunan Provincial People's Hospital, the First Affiliated Hospital of Hunan Normal University, Changsha, P.R. China
⨯
Huilan Rao,

Affiliation Department of Pathology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, P.R. China
⨯
Mengfei Yao,

Affiliation Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, P.R. China
⨯
Liyang Hu

Affiliation Department of Medical Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, P.R. China
⨯

The Effect of Prophylactic Lamivudine plus Adefovir Therapy Compared with Lamivudine Alone in Preventing Hepatitis B Reactivation in Lymphoma Patients with High Baseline HBV DNA during Chemotherapy

Qingqing Cai,
Kailin Chen,
Jie Chen,
Shaoxu Wu,
Qirong Geng,
Huiqiang Huang,
Tongyu Lin,
Wenqi Jiang,
Zhongjun Xia,
Huaxin Duan

Published: October 6, 2016
https://doi.org/10.1371/journal.pone.0164210

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