Hemizygous Deletion on Chromosome 3p26.1 Is Associated with Heavy Smoking among African American Subjects in the COPDGene Study

Ferdouse Begum; Ingo Ruczinski; John E. Hokanson; Sharon M. Lutz; Margaret M. Parker; Michael H. Cho; Jacqueline B. Hetmanski; Robert B. Scharpf; James D. Crapo; Edwin K. Silverman; Terri H. Beaty

doi:10.1371/journal.pone.0164134

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Open Access

Peer-reviewed

Research Article

Hemizygous Deletion on Chromosome 3p26.1 Is Associated with Heavy Smoking among African American Subjects in the COPDGene Study

Ferdouse Begum ,

* E-mail: fbegum1@jhu.edu

Affiliation Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

http://orcid.org/0000-0001-7835-8051

⨯
Ingo Ruczinski,

Affiliation Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
⨯
John E. Hokanson,

Affiliation Department of Epidemiology, Colorado School of Public Health, Aurora, Colorado, United States of America
⨯
Sharon M. Lutz,

Affiliation Department of Biostatisitics and Informatics, Colorado School of Public Health, Aurora, Colorado, United States of America
⨯
Margaret M. Parker,

Affiliation Channing Division of Network Medicine and Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Michael H. Cho,

Affiliation Channing Division of Network Medicine and Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Jacqueline B. Hetmanski,

Affiliation Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
⨯
Robert B. Scharpf,

Affiliation Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
James D. Crapo,

Affiliation Department of Medicine, National Jewish Health, Denver, Colorado, United States of America
⨯
Edwin K. Silverman,

Affiliation Channing Division of Network Medicine and Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Terri H. Beaty

Affiliation Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
⨯

Hemizygous Deletion on Chromosome 3p26.1 Is Associated with Heavy Smoking among African American Subjects in the COPDGene Study

Ferdouse Begum,
Ingo Ruczinski,
John E. Hokanson,
Sharon M. Lutz,
Margaret M. Parker,
Michael H. Cho,
Jacqueline B. Hetmanski,
Robert B. Scharpf,
James D. Crapo,
Edwin K. Silverman

Published: October 6, 2016
https://doi.org/10.1371/journal.pone.0164134

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