Treatment Selection Choices Should Not Be Based on Benefits or Costs Alone: A Head-to-Head Randomized Controlled Trial of Antiviral Drugs for Hepatitis C

Perica Davitkov; Apoorva Krishna Chandar; Amy Hirsch; Anita Compan; Marina G. Silveira; Donald D. Anthony; Suzanne Smith; Clare Gideon; Robert A. Bonomo; Yngve Falck-Ytter

doi:10.1371/journal.pone.0163945

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Research Article

Treatment Selection Choices Should Not Be Based on Benefits or Costs Alone: A Head-to-Head Randomized Controlled Trial of Antiviral Drugs for Hepatitis C

Perica Davitkov,

Affiliations Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, United States of America, University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Case Western Reserve University, Cleveland, Ohio, United States of America
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Apoorva Krishna Chandar,

Affiliations Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, United States of America, University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Case Western Reserve University, Cleveland, Ohio, United States of America
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Amy Hirsch,

Affiliations Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, United States of America, Geriatric Research Education and Clinical Center (GRECC), Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, United States of America
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Anita Compan,

Affiliation Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, United States of America
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Marina G. Silveira,

Affiliations Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, United States of America, University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Case Western Reserve University, Cleveland, Ohio, United States of America
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Donald D. Anthony,

Affiliations Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, United States of America, University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Case Western Reserve University, Cleveland, Ohio, United States of America
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Suzanne Smith,

Affiliation Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, United States of America
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Clare Gideon,

Affiliation Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, United States of America
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Robert A. Bonomo,

Affiliations Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, United States of America, University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Case Western Reserve University, Cleveland, Ohio, United States of America, Geriatric Research Education and Clinical Center (GRECC), Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, United States of America
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Yngve Falck-Ytter

* E-mail: Yngve.Falck-Ytter@case.edu

Affiliations Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, United States of America, University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Case Western Reserve University, Cleveland, Ohio, United States of America, Geriatric Research Education and Clinical Center (GRECC), Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, United States of America
⨯

Treatment Selection Choices Should Not Be Based on Benefits or Costs Alone: A Head-to-Head Randomized Controlled Trial of Antiviral Drugs for Hepatitis C

Perica Davitkov,
Apoorva Krishna Chandar,
Amy Hirsch,
Anita Compan,
Marina G. Silveira,
Donald D. Anthony,
Suzanne Smith,
Clare Gideon,
Robert A. Bonomo,
Yngve Falck-Ytter

Published: October 14, 2016
https://doi.org/10.1371/journal.pone.0163945

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Protease inhibitor therapy
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Adverse events
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Drug therapy
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Antiviral therapy
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Randomized controlled trials
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Hepatitis C virus
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Hepatitis C
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