Viral Inhibition of Bacterial Phagocytosis by Human Macrophages: Redundant Role of CD36

Grace E. Cooper; Zoe C. Pounce; Joshua C. Wallington; Leidy Y. Bastidas-Legarda; Ben Nicholas; Chiamaka Chidomere; Emily C. Robinson; Kirstin Martin; Anna S. Tocheva; Myron Christodoulides; Ratko Djukanovic; Tom M. A. Wilkinson; Karl J. Staples

doi:10.1371/journal.pone.0163889

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Open Access

Peer-reviewed

Research Article

Viral Inhibition of Bacterial Phagocytosis by Human Macrophages: Redundant Role of CD36

Grace E. Cooper,

Affiliation Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom
⨯
Zoe C. Pounce,

Affiliation Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom
⨯
Joshua C. Wallington,

Affiliation Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom
⨯
Leidy Y. Bastidas-Legarda,

Affiliation Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom
⨯
Ben Nicholas,

Affiliation Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom
⨯
Chiamaka Chidomere,

Affiliation Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom
⨯
Emily C. Robinson,

Affiliation Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom
⨯
Kirstin Martin,

Affiliation Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom
⨯
Anna S. Tocheva,

Affiliation Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom
⨯
Myron Christodoulides,

Affiliation Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom
⨯
Ratko Djukanovic,

Affiliations Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom, Southampton NIHR Respiratory Biomedical Research Unit, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom
⨯
Tom M. A. Wilkinson,

Affiliations Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom, Southampton NIHR Respiratory Biomedical Research Unit, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom
⨯
Karl J. Staples

* E-mail: k.staples@southampton.ac.uk

Affiliation Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom

http://orcid.org/0000-0003-3844-6457

⨯

Viral Inhibition of Bacterial Phagocytosis by Human Macrophages: Redundant Role of CD36

Grace E. Cooper,
Zoe C. Pounce,
Joshua C. Wallington,
Leidy Y. Bastidas-Legarda,
Ben Nicholas,
Chiamaka Chidomere,
Emily C. Robinson,
Kirstin Martin,
Anna S. Tocheva,
Myron Christodoulides

Published: October 4, 2016
https://doi.org/10.1371/journal.pone.0163889

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Influenza
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Macrophages
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Flow cytometry
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Small interfering RNA
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