Evaluation of Resistance-Associated Substitutions in NS5A Using Direct Sequence and Cycleave Method and Treatment Outcome with Daclatasvir and Asunaprevir for Chronic Hepatitis C Genotype 1

• Tatsuya Ide ,

  Contributed equally to this work with: Tatsuya Ide, Yuichiro Eguchi, Masaru Harada

  * E-mail: ide@med.kurume-u.ac.jp

  Affiliation Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka, Japan

  http://orcid.org/0000-0003-4106-6527

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• Yuichiro Eguchi ,

  Contributed equally to this work with: Tatsuya Ide, Yuichiro Eguchi, Masaru Harada

  Affiliation Department of Internal Medicine, Saga Medical School, Saga, Japan

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• Masaru Harada ,

  Contributed equally to this work with: Tatsuya Ide, Yuichiro Eguchi, Masaru Harada

  Affiliation Third Department of Internal Medicine, University of Occupational and Environmental Health, Fukuoka, Japan

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• Kunihide Ishii,

  Affiliation Asakura Medical Association Hospital, Fukuoka, Japan

  ⨯
• Masaru Morita,

  Affiliation Yame General Hospital, Fukuoka, Japan

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• Yasuyo Morita,

  Affiliation Nagata Hospital, Fukuoka, Japan

  ⨯
• Gen Sugiyama,

  Affiliation Kurume University Medical Center, Fukuoka, Japan

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• Hirofumi Fukushima,

  Affiliation Saiseikai Futsukaichi Hospital, Fukuoka, Japan

  ⨯
• Yoichi Yano,

  Affiliation Saga Central Hospital, Saga, Japan

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• Kazunori Noguchi,

  Affiliation Omuta City Hospital, Fukuoka, Japan

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• Hiroki Nakamura,

  Affiliation Shin Koga Clinic, Fukuoka, Japan

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• Junjiro Hisatomi,

  Affiliation Kurume Chuo Hosipital, Fukuoka, Japan

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• Hiroto Kumemura,

  Affiliation Kumamoto Central Hospital, Kumamoto, Japan

  ⨯
• Miki Shirachi,

  Affiliation Chikugo City Hospital, Fukuoka, Japan

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• Shinji Iwane,

  Affiliation Department of Internal Medicine, Saga Medical School, Saga, Japan

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• Michiaki Okada,

  Affiliation Department of Internal Medicine, Saga Medical School, Saga, Japan

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• Yuichi Honma,

  Affiliation Third Department of Internal Medicine, University of Occupational and Environmental Health, Fukuoka, Japan

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• Teruko Arinaga-Hino,

  Affiliation Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka, Japan

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• Ichiro Miyajima,

  Affiliation Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka, Japan

  ⨯
• Kei Ogata,

  Affiliation Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka, Japan

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• Reiichiro Kuwahara,

  Affiliation Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka, Japan

  ⨯
• Keisuke Amano,

  Affiliation Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka, Japan

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• Toshihiro Kawaguchi,

  Affiliation Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka, Japan

  ⨯
• Ryoko Kuromatsu,

  Affiliation Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka, Japan

  ⨯
• Takuji Torimura,

  Affiliation Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka, Japan

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•  [ ... ],
• DAAs Multicenter Study Group

  ¶Membership of the The DAAs Multicenter Study Group is provided in the Acknowledgments.

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